CAJ | 학술논문

目的：观察母牛分枝杆菌菌苗辅助抗结核治疗结核性多浆膜腔积液的疗效。方法将96例结核性多浆膜腔积液患者按随机分组方法分为观察组47例和对照组49例，两组均采用3HREZ/15HRE方案进行抗结核治疗，观察组在此基础上加用母牛分支杆菌菌苗肌肉注射。结果观察组治愈32例（68.09%），有效13例（27.66%），无效2例（4.26%）；对照组治愈20例（40.82%），有效20例（40.82%），无效9例（18.36%）。观察组治愈率明显高于对照组（ P<0.05）。结论在传统抗结核药物治疗结核性多浆膜腔积液的基础上，联合使用母牛分枝杆菌菌苗，疗效明显优于单纯的传统抗结核药物治疗。
목적：관찰모우분지간균균묘보조항결핵치료결핵성다장막강적액적료효。방법장96례결핵성다장막강적액환자안수궤분조방법분위관찰조47례화대조조49례，량조균채용3HREZ/15HRE방안진행항결핵치료，관찰조재차기출상가용모우분지간균균묘기육주사。결과관찰조치유32례（68.09%），유효13례（27.66%），무효2례（4.26%）；대조조치유20례（40.82%），유효20례（40.82%），무효9례（18.36%）。관찰조치유솔명현고우대조조（ P<0.05）。결론재전통항결핵약물치료결핵성다장막강적액적기출상，연합사용모우분지간균균묘，료효명현우우단순적전통항결핵약물치료。
Objective To observe the effect of Mycobacterium vaccae vaccine in auxiliary anti-tuberculosis treatment of tuberculous pol-yserositis. Methods 96 cases of tuberculous polyserositis were randomized divided into the observation group ( 47 cases ) and the control group ( 49 cases ) . The two groups were treated by the 3HREZ/15HRE anti-tuberculosis treatment schemes. On this basis the observa-tion group was add with Mycobacterium vaccae vaccine by intramuscular injection. Results Among 47 cases in the observation group, 32 cases ( 68. 09%) were cured, 13 cases ( 27. 66%) were effective and 2 cases ( 4. 26%) were ineffective;among 49 cases in the con-trol group, 20 cases ( 40. 82%) were cured, 20 cases ( 40. 82%) were effective and 9 cases ( 18. 36% ) were ineffective, the cure rate of the observation group was significantly higher than that of the control group with statistical difference ( P<0. 05 ) . Conclusion The com-bination use of Mycobacterium vaccae vaccine and the traditional anti-tuberculosis drugs has significantly better effect than the tradi-tional anti-tuberculosis drugs alone for treating tuberculous polyserositis.