中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2014年
22期
42-44
,共3页
广藿香%百秋李醇%广藿香酮%提取工艺%产地
廣藿香%百鞦李醇%廣藿香酮%提取工藝%產地
엄곽향%백추리순%엄곽향동%제취공예%산지
Pogostemon cablin%patchouli alcohol%patchoulenone%extraction process%habitat
目的：优化广藿香挥发油的提取工艺，建立同时测定广藿香酮和百秋李醇含量的方法，比较不同产地广藿香药材的质量。方法采用正交试验考察广藿香挥发油的最佳提取工艺；采用气相色谱法同时测定不同产地广藿香挥发油中百秋李醇和广藿香酮的含量，以百秋李醇和广藿香酮的总含量与挥发油收率为指标评价不同产地广藿香药材的质量。结果广藿香挥发油最佳提取工艺为加8倍量水浸泡4 h，蒸馏提取4 h；建立的含量测定方法线性关系良好，准确度高，稳定可靠。结论优选的提取工艺科学合理，适合广藿香挥发油的工业化生产；建立的百秋李醇和广藿香酮测定方法准确可靠、易于操作、重复性好，适用于广藿香药材的质量控制；5个不同产地的广藿香药材在挥发油收率、百秋李醇和广藿香酮总含量等的差异均较大。
目的：優化廣藿香揮髮油的提取工藝，建立同時測定廣藿香酮和百鞦李醇含量的方法，比較不同產地廣藿香藥材的質量。方法採用正交試驗攷察廣藿香揮髮油的最佳提取工藝；採用氣相色譜法同時測定不同產地廣藿香揮髮油中百鞦李醇和廣藿香酮的含量，以百鞦李醇和廣藿香酮的總含量與揮髮油收率為指標評價不同產地廣藿香藥材的質量。結果廣藿香揮髮油最佳提取工藝為加8倍量水浸泡4 h，蒸餾提取4 h；建立的含量測定方法線性關繫良好，準確度高，穩定可靠。結論優選的提取工藝科學閤理，適閤廣藿香揮髮油的工業化生產；建立的百鞦李醇和廣藿香酮測定方法準確可靠、易于操作、重複性好，適用于廣藿香藥材的質量控製；5箇不同產地的廣藿香藥材在揮髮油收率、百鞦李醇和廣藿香酮總含量等的差異均較大。
목적：우화엄곽향휘발유적제취공예，건립동시측정엄곽향동화백추리순함량적방법，비교불동산지엄곽향약재적질량。방법채용정교시험고찰엄곽향휘발유적최가제취공예；채용기상색보법동시측정불동산지엄곽향휘발유중백추리순화엄곽향동적함량，이백추리순화엄곽향동적총함량여휘발유수솔위지표평개불동산지엄곽향약재적질량。결과엄곽향휘발유최가제취공예위가8배량수침포4 h，증류제취4 h；건립적함량측정방법선성관계량호，준학도고，은정가고。결론우선적제취공예과학합리，괄합엄곽향휘발유적공업화생산；건립적백추리순화엄곽향동측정방법준학가고、역우조작、중복성호，괄용우엄곽향약재적질량공제；5개불동산지적엄곽향약재재휘발유수솔、백추리순화엄곽향동총함량등적차이균교대。
Objective To optimize the extraction process of patchouli volatile oil,to establish a simultaneous determination method of the patchoulenone and patchouli alcohol contents,and to compare the qualities of the Pogostemon cablin from different habitats. Methods The optimal extraction technology of patchouli volatile oil was determined with the orthogonal experiment;the gas chromatography method was adopted to simultaneously determining the content of patchoulenone and patchouli alcohol. The qualities of the patchouli medicinal material from different habitats were evaluated by the total content of patchoulenone and patchouli alcohol,as well as the yield of volatile oil. Results The optimal extraction of patchouli volatile oil was adding 8 times the amount of water,soaking for 4 h,then con-ducting distillation extraction for 4 h;the established content determination method had good linearity and high accuracy,and was stable and reliable. Conclusion The optimized extraction technology is scientific and reasonable and suitable for the industrialized production of patchouli volatile oil;the established the content determination method of patchoulenone and patchouli alcohol is accurate,reliable and easy to operate with good reproducibility,which is suitable for the quality control of Pogostemon cablin;Pogostemon cablin from 5 dif-ferent habitats has great differences in the aspects of yield of volatile oil and the total contents of patchoulenone and patchouli alcohol.
