中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2014年
22期
35-36
,共2页
白及%多糖%药物分析
白及%多糖%藥物分析
백급%다당%약물분석
Bletilla striata%polysaccharide%pharmaceutical analysis
目的:探讨白及多糖的分离纯化、结构,研究理化性质。方法对白及多糖进行提取和分离纯化,对BR4进行纯度鉴定、相对分子质量测定,进行理化性质、单糖组分和红外光谱分析。结果白及多糖BR4是一种白色系纤维状物质,为中性,含有H元素和C元素,单一组分,相对分子质量为99658;含葡萄糖和甘露糖2种单糖,其相对含量为3:4.8,红外光谱分析存在吡喃型糖基和甘露糖基。结论通过对白及多糖的药物结构分析,使其医学和临床应用能有更好的前景。
目的:探討白及多糖的分離純化、結構,研究理化性質。方法對白及多糖進行提取和分離純化,對BR4進行純度鑒定、相對分子質量測定,進行理化性質、單糖組分和紅外光譜分析。結果白及多糖BR4是一種白色繫纖維狀物質,為中性,含有H元素和C元素,單一組分,相對分子質量為99658;含葡萄糖和甘露糖2種單糖,其相對含量為3:4.8,紅外光譜分析存在吡喃型糖基和甘露糖基。結論通過對白及多糖的藥物結構分析,使其醫學和臨床應用能有更好的前景。
목적:탐토백급다당적분리순화、결구,연구이화성질。방법대백급다당진행제취화분리순화,대BR4진행순도감정、상대분자질량측정,진행이화성질、단당조분화홍외광보분석。결과백급다당BR4시일충백색계섬유상물질,위중성,함유H원소화C원소,단일조분,상대분자질량위99658;함포도당화감로당2충단당,기상대함량위3:4.8,홍외광보분석존재필남형당기화감로당기。결론통과대백급다당적약물결구분석,사기의학화림상응용능유경호적전경。
Objective To research the isolation and purification of polysaccharide from Bletilla striata,its structure and physicochemical properties. Methods The Bletilla striata polysaccharide(BR4)was extracted and purified,its purity was identified,the relative molecular mass was determined,and then the analysis of the physicochemical properties,monosaccharide components and infrared spectroscopy were conducted. Results BR4 is a kind of white fibrillar substance,neutral in character,containing H and C elements,single component,the relative molecular weight of 99 658,containing the 2 kinds of monosaccharide of glucose and mannose,their relative contents were 3:4. 8, the infrared spectroscopic analysis showed the existence of pyran glycosyl and mannose glycosyl. Conclusion Through the analysis of the medicine structure of BR4,its medical and clinical application can have better prospects.