CAJ | 학술논문

目的：探讨氯吡格雷、阿司匹林联合阿托伐他汀治疗短暂性脑缺血发作的临床疗效。方法选取2009年6月至2013年6月住院治疗的短暂性脑缺血发作患者150例，随机分为对照组和观察组，各75例，对照组采用阿司匹林+氯吡格雷治疗，观察组在对照组用药基础上联合阿托伐他汀治疗。结果观察组总有效率为92.00%，明显高于对照组的73.33%（ P<0.05），治疗期间未出现明显的出血倾向及横纹肌溶解等严重并发症。结论氯吡格雷、阿司匹林联合阿托伐他汀治疗短暂性脑缺血发作的效果明显优于氯吡格雷、阿司匹林，且方法简便，安全可靠。
목적：탐토록필격뢰、아사필림연합아탁벌타정치료단잠성뇌결혈발작적림상료효。방법선취2009년6월지2013년6월주원치료적단잠성뇌결혈발작환자150례，수궤분위대조조화관찰조，각75례，대조조채용아사필림+록필격뢰치료，관찰조재대조조용약기출상연합아탁벌타정치료。결과관찰조총유효솔위92.00%，명현고우대조조적73.33%（ P<0.05），치료기간미출현명현적출혈경향급횡문기용해등엄중병발증。결론록필격뢰、아사필림연합아탁벌타정치료단잠성뇌결혈발작적효과명현우우록필격뢰、아사필림，차방법간편，안전가고。
Objective To investigate the clinical effect of clopidogrel and aspirin combined with atorvastatin in treating transient ischemic attack. Methods 150 inpatients with transient ischemic attack admitted to our hospital from June 2009 to June 2013 were selected and randomly divided into the control group and the observation group,75 cases in each group. The control group was treated by aspirin plus clopidogrel,while on this basis the observation group was added atorvastatin. Results The total effective rate was 92. 00% in the observation group which was significantly higher than 73. 33% in the control group( P < 0. 05). No serious complications of bleeding tendency and rhabdomyolysis occurred during treatment in the two groups. Conclusion Clopidogrel and aspirin combined with atorvas-tatin is superior to clopidogrel and aspirin group in the effect for treating transient ischemic attack,moreover this method is simple,con-venient,safe and reliable.