转化医学电子杂志
轉化醫學電子雜誌
전화의학전자잡지
2014年
6期
116-117,119
,共3页
张红明%李静%孙嘉俊%王雪松
張紅明%李靜%孫嘉俊%王雪鬆
장홍명%리정%손가준%왕설송
复方甘草酸苷片%胶原蛋白面膜%激素依赖性皮炎%疗效观察
複方甘草痠苷片%膠原蛋白麵膜%激素依賴性皮炎%療效觀察
복방감초산감편%효원단백면막%격소의뢰성피염%료효관찰
glycyrrhizin tablets%collagen mask%Hormone-De-pendent Dermatitis%efficacy observation
目的：观察复方甘草酸苷片联合胶原蛋白面膜治疗面部激素依赖性皮炎的效果，为临床提供帮助和指导．方法：将我院2013-06／2014-06皮肤科门诊收治的80例面部激素依赖性皮炎患者随机分为治疗组和对照组，对照组给予胶原蛋白面膜治疗，20～30 min／次，1次／d，连续使用两周；治疗组在对照组胶原蛋白面膜治疗基础上加用复方甘草酸苷片（商品名派甘能、丽君制药）2片／次、3次／d，口服．治疗6周后，观察两组患者的疗效．结果：对照组总有效率为45％，而治疗组患者高达87．5％，差异具有统计学意义（P＜0．05）．两组患者在痊愈、有效、无效方面，差异均具有统计学意义（χ2＝16．1565，P＜0．01）．对照组与治疗组分别有3例患者出现血钾轻微下降症状，口服补钾后缓解．结论：复方甘草酸苷片联合胶原蛋白敷料面膜对激素依赖性皮炎的治疗，不仅能够改善皮肤症状，还能够增加抗炎和抗过敏作用，两药联合使用，提高治疗效果，减少了不良反应发生．
目的：觀察複方甘草痠苷片聯閤膠原蛋白麵膜治療麵部激素依賴性皮炎的效果，為臨床提供幫助和指導．方法：將我院2013-06／2014-06皮膚科門診收治的80例麵部激素依賴性皮炎患者隨機分為治療組和對照組，對照組給予膠原蛋白麵膜治療，20～30 min／次，1次／d，連續使用兩週；治療組在對照組膠原蛋白麵膜治療基礎上加用複方甘草痠苷片（商品名派甘能、麗君製藥）2片／次、3次／d，口服．治療6週後，觀察兩組患者的療效．結果：對照組總有效率為45％，而治療組患者高達87．5％，差異具有統計學意義（P＜0．05）．兩組患者在痊愈、有效、無效方麵，差異均具有統計學意義（χ2＝16．1565，P＜0．01）．對照組與治療組分彆有3例患者齣現血鉀輕微下降癥狀，口服補鉀後緩解．結論：複方甘草痠苷片聯閤膠原蛋白敷料麵膜對激素依賴性皮炎的治療，不僅能夠改善皮膚癥狀，還能夠增加抗炎和抗過敏作用，兩藥聯閤使用，提高治療效果，減少瞭不良反應髮生．
목적：관찰복방감초산감편연합효원단백면막치료면부격소의뢰성피염적효과，위림상제공방조화지도．방법：장아원2013-06／2014-06피부과문진수치적80례면부격소의뢰성피염환자수궤분위치료조화대조조，대조조급여효원단백면막치료，20～30 min／차，1차／d，련속사용량주；치료조재대조조효원단백면막치료기출상가용복방감초산감편（상품명파감능、려군제약）2편／차、3차／d，구복．치료6주후，관찰량조환자적료효．결과：대조조총유효솔위45％，이치료조환자고체87．5％，차이구유통계학의의（P＜0．05）．량조환자재전유、유효、무효방면，차이균구유통계학의의（χ2＝16．1565，P＜0．01）．대조조여치료조분별유3례환자출현혈갑경미하강증상，구복보갑후완해．결론：복방감초산감편연합효원단백부료면막대격소의뢰성피염적치료，불부능구개선피부증상，환능구증가항염화항과민작용，량약연합사용，제고치료효과，감소료불량반응발생．
AIM:To observe treatment effect of facial glycyrrhi-zin tablets joint collagen mask on Hormone-Dependent Dermatitis and to provide clinical help and guidance.METHODS:The 80 cases of our hospital from June 2013 to June 2014 with Hormone-Dependent Dermatitis were randomly divided into treatment group and control group.The control group received collagen mask treat-ment,20 ~30 min /time,one time /day,continuously use of two weeks;treatment group received collagen mask treatment based on the use of glycyrrhizin tablets (named Paiganneng,Lijun Pharmaceutical)2 tablets/time,3 times/day,orally.After 6 weeks' treatment efficacy of the two groups were observed.RE-SULTS:In the control group,the total effective rate was 45%, while the treatment group was up to 87.5%,the difference was statistically significant (P<0.05).Two groups of patients' cured rate,valid rate,invalid rate,had statistically significant differ-ence (χ2 =16.1565,P<0.01).The control group and the treat-ment group each had three cases of patients with symptoms of a slight decrease in serum potassium,oral potassium remission. CONCLUSION:Glycyrrhizin tablets joint collagen dressings mask for the treatment of Hormone-Dependent Dermatitis,can not only improve the skin symptoms,but also increase the anti-in-flammatory and anti-allergic effects,two drugs used in combina-tion can improve the therapeutic effect,and reduce the incidence of adverse reactions.
