CAJ | 학술논문

目的：了解孕妇生殖道无乳链球菌携带及耐药状况，为临床用药提供依据。方法取孕妇阴道分泌物标本进行细菌培养，分离出的无乳链球菌经 VITEK 2全自动细菌鉴定分析仪进行鉴定和药物敏感试验。结果1042份标本中分离出无乳链球菌56例，分离率为5.4％。药物敏感试验结果显示无乳链球菌对青霉素、头孢唑啉、万古霉素、利奈唑烷、呋喃妥因均高度敏感，未发现中介或耐药菌株；左旋氧氟沙星、莫西沙星及克林霉素、红霉素、四环素的敏感率分别为84.0％、84.0％、71.4％、39.3％和8.9％。结论该院孕妇无乳链球菌的携带率不高，青霉素和头孢唑啉可作为治疗的首选药。临床和实验室应重视孕妇无乳链球菌的检测。
목적：료해잉부생식도무유련구균휴대급내약상황，위림상용약제공의거。방법취잉부음도분비물표본진행세균배양，분리출적무유련구균경 VITEK 2전자동세균감정분석의진행감정화약물민감시험。결과1042빈표본중분리출무유련구균56례，분리솔위5.4％。약물민감시험결과현시무유련구균대청매소、두포서람、만고매소、리내서완、부남타인균고도민감，미발현중개혹내약균주；좌선양불사성、막서사성급극림매소、홍매소、사배소적민감솔분별위84.0％、84.0％、71.4％、39.3％화8.9％。결론해원잉부무유련구균적휴대솔불고，청매소화두포서람가작위치료적수선약。림상화실험실응중시잉부무유련구균적검측。
Objective To understand the carrying status and drug resistance of streptococcus agalactiae in the genital tract of pregnant women.Methods The vaginal discharge from pregnant women was collected for conducting the bacterial culture.The iso-lated streptococcus agalactiae was performed the identification and the drugs susceptibility test by the VITEK 2 fully automatice bacterial identification analyzer.Results Among 1 042 samples,streptococcus agalactiae was isolated in 6 cases with the separation rate of 5.4%.The drug sensitivity test showed the Streptococcus agalactiae was highly sensitive to penicillin,cefazolin,vancomycin, linezolid and nitrofurantoin.The intermediate strains or drug resistant strains were not found.The sensitive rate to levofloxacin, moxifloxacin and clindamycin,erythromycin,tetracycline were 84.0%,84.0%,71.4%,39.3% and 8.9% respectively.Conclusion The carrying rate of streptococcus agalactiae in pregnant women is not high in our hospital.Penicillin and cefazolin should be as the drug of first choice for therapy and the clincal and laboratory nould payattention to detection of streptococcus agalactiae in pregnant women.