国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
23期
3217-3219
,共3页
变应性鼻炎%过敏原%儿童
變應性鼻炎%過敏原%兒童
변응성비염%과민원%인동
allergic rhinitis%allergen%children
目的：分析常州地区过敏性鼻炎患儿吸入性过敏原检测结果及不同年龄组过敏原分布情况。方法采用德国敏筛过敏原检侧系统（Allergy Screen）测定473例0～12岁过敏性鼻炎患儿血清中过敏原特异性 IgE 抗体水平。根据年龄分为婴幼儿组（0～3岁）、学龄前儿童（4～6岁）和学龄儿童（7～12岁），并比较不同年龄组过敏原阳性率及变化趋势。结果473例患儿过敏原阳性340例（71.9％），前三位过敏原分别是户尘螨（55.6％）、混合真菌（25.8％）和屋尘（18.8％），随年龄增长阳性率均呈升高趋势。其中户尘螨（χ2＝21.061，P ＝0.000）、屋尘（χ2＝15.111，P ＝0.000）和猫狗毛皮屑（χ2＝7.597，P ＝0.022）组间分布比较差异有统计学意义。单一过敏原阳性率最高（38.5％），第二位为双重过敏原阳性（23.7％）。单一过敏原阳性前三位与各类过敏原总体阳性排序相同。最常见双重过敏原是户尘螨＋屋尘组合，多重过敏原阳性率组间分布差异有统计学意义（χ2＝13.399，P ＝0.001）。结论常州地区过敏性鼻炎患儿吸入性过敏原以户尘螨、混合真菌和屋尘为主，阳性率随年龄增长呈上升趋势，不同年龄组过敏原构成有差异，单一过敏原阳性最常见，其次为双重过敏原阳性。
目的：分析常州地區過敏性鼻炎患兒吸入性過敏原檢測結果及不同年齡組過敏原分佈情況。方法採用德國敏篩過敏原檢側繫統（Allergy Screen）測定473例0～12歲過敏性鼻炎患兒血清中過敏原特異性 IgE 抗體水平。根據年齡分為嬰幼兒組（0～3歲）、學齡前兒童（4～6歲）和學齡兒童（7～12歲），併比較不同年齡組過敏原暘性率及變化趨勢。結果473例患兒過敏原暘性340例（71.9％），前三位過敏原分彆是戶塵螨（55.6％）、混閤真菌（25.8％）和屋塵（18.8％），隨年齡增長暘性率均呈升高趨勢。其中戶塵螨（χ2＝21.061，P ＝0.000）、屋塵（χ2＝15.111，P ＝0.000）和貓狗毛皮屑（χ2＝7.597，P ＝0.022）組間分佈比較差異有統計學意義。單一過敏原暘性率最高（38.5％），第二位為雙重過敏原暘性（23.7％）。單一過敏原暘性前三位與各類過敏原總體暘性排序相同。最常見雙重過敏原是戶塵螨＋屋塵組閤，多重過敏原暘性率組間分佈差異有統計學意義（χ2＝13.399，P ＝0.001）。結論常州地區過敏性鼻炎患兒吸入性過敏原以戶塵螨、混閤真菌和屋塵為主，暘性率隨年齡增長呈上升趨勢，不同年齡組過敏原構成有差異，單一過敏原暘性最常見，其次為雙重過敏原暘性。
목적：분석상주지구과민성비염환인흡입성과민원검측결과급불동년령조과민원분포정황。방법채용덕국민사과민원검측계통（Allergy Screen）측정473례0～12세과민성비염환인혈청중과민원특이성 IgE 항체수평。근거년령분위영유인조（0～3세）、학령전인동（4～6세）화학령인동（7～12세），병비교불동년령조과민원양성솔급변화추세。결과473례환인과민원양성340례（71.9％），전삼위과민원분별시호진만（55.6％）、혼합진균（25.8％）화옥진（18.8％），수년령증장양성솔균정승고추세。기중호진만（χ2＝21.061，P ＝0.000）、옥진（χ2＝15.111，P ＝0.000）화묘구모피설（χ2＝7.597，P ＝0.022）조간분포비교차이유통계학의의。단일과민원양성솔최고（38.5％），제이위위쌍중과민원양성（23.7％）。단일과민원양성전삼위여각류과민원총체양성배서상동。최상견쌍중과민원시호진만＋옥진조합，다중과민원양성솔조간분포차이유통계학의의（χ2＝13.399，P ＝0.001）。결론상주지구과민성비염환인흡입성과민원이호진만、혼합진균화옥진위주，양성솔수년령증장정상승추세，불동년령조과민원구성유차이，단일과민원양성최상견，기차위쌍중과민원양성。
Objective To analyze the results of inhaled allergens detection in children with allergic rhinitis(AR)in Changzhou ar-ea and the distribution situation of allergens in different age groups.Methods The levels of serum allergen specific IgE antibodies in 473 children cases(aged 1-12 years)of allergic rhinitis(AR)were detected by the Allergy Screen allergen screen system.The children cases were divided into the infants group(0-3 years old),preschool children(4-6 years old)and school age children(7 -12 years old)according to age.The allergen positive rates and the change tendency were compared among different age groups.Re-sults Among 473 children cases of allergic rhinitis,340 cases(71.9%)were positive.The top three allergens were house dust mite (55.6%),mixed fungi(25.8%)and house dust(18.8%).The positive rate of allergen showed the upward trend with the age in-crease.The distribution of house dust mite(χ2 =21.061,P =0.000),house dust (χ2 =15.111,P =0.000)and the cat and dog dan-der(χ2 = 7.597,P = 0.022 )was statistically significant among the three groups.Single allergen positive rate was the highest (38.5%)and the secand was double allergens(23.7%).The top three positive in single allergens was consistent with sort of total allergen positive rate.The most common double allergen was the combination of house dust mites and house dust.The multiple al-lergen positive rate had statistical significance in the distribution among groups(χ2 =13.399,P =0.001).Conclusion The inhaled allergens of AR children in Changzhou area are dominated by house dust mite,mixed fungi and house dust.The positive rate shows the increasing trend with age increase.The allergen constituents are different in different age groups.The positive single allergen is most common,followed by positive double allergens.
