CAJ | 학술논문

目的：了解盐城市盐都区高危人群梅毒感染状况，为预防和干预提供科学依据。方法采用 ELISA 法检测 TP 抗体，TP 抗体阳性者用梅毒螺旋体抗体明胶颗粒凝集试验（TPPA）进行复检，确认阳性者再作梅毒快速血浆反应素试验（RPR）。结果高危人群梅毒抗体阳性率为14.30％，梅毒感染者中 RPR 阳性率为58.18％；不同人群、不同年龄组性别梅毒抗体阳性率经统计学分析差异有统计学意义（P ＜0.05）。结论盐都区高危人群梅毒感染率高，性病门诊就诊者、劳教收容人员感染率均高于艾滋病自愿咨询检测（VCT）者；21～40岁女性感染率明显高于男性。应加强高危人群监测，开展宣传教育和行为干预，从而有效遏制梅毒在人群中的传播。
목적：료해염성시염도구고위인군매독감염상황，위예방화간예제공과학의거。방법채용 ELISA 법검측 TP 항체，TP 항체양성자용매독라선체항체명효과립응집시험（TPPA）진행복검，학인양성자재작매독쾌속혈장반응소시험（RPR）。결과고위인군매독항체양성솔위14.30％，매독감염자중 RPR 양성솔위58.18％；불동인군、불동년령조성별매독항체양성솔경통계학분석차이유통계학의의（P ＜0.05）。결론염도구고위인군매독감염솔고，성병문진취진자、로교수용인원감염솔균고우애자병자원자순검측（VCT）자；21～40세녀성감염솔명현고우남성。응가강고위인군감측，개전선전교육화행위간예，종이유효알제매독재인군중적전파。
Objective To understand the syphilis infection status of high-risk population in Yangdu district of Yancheng city so as to provide a scientific basis for preventive and intervention measures.Methods Serum anti-TP antibody was detected by the en-zyme-linked immunosorbent assays(ELISA).Treponema pallidum particle agglutination(TPPA)assay was carried out on the posi-tive samples of anti-TP antibody,then rapid plasma regain(RPR)was conducted on the positive ones.Results The syphilis antibody positive rate of high-risk population was 14.30%,among them the positive rate of RPR in the syphilis infected persons was 58.18%;the positive rate of syphilis had statistically significant difference between genders in different crowds and different age groups(P <0.05).Conclusion The syphilis infection rate of high-risk population in Yandu district is high.The infection rates of STD clinic clients and the people subjected to reeducation were higher than those of the person accepting voluntary counseling and testing(VCT);the infection rate of 21-40 years old females is significantly higher than that of males.The high-risk population mo-nitoring should be strengthened and the publicity and education and behavior intervention should be carried out to effectively re-strain the spread of syphilis in crowds.