国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
23期
3207-3209
,共3页
曾劲峰%陈云龙%郑欣%刘衡%邬林枫%杜丹丹
曾勁峰%陳雲龍%鄭訢%劉衡%鄔林楓%杜丹丹
증경봉%진운룡%정흔%류형%오림풍%두단단
反应性%献血者归队%乙肝表面抗原%抗-HCV
反應性%獻血者歸隊%乙肝錶麵抗原%抗-HCV
반응성%헌혈자귀대%을간표면항원%항-HCV
reactive%rejoin of blood donors%hepatitis B surface antigen%anti-HCV
目的:探讨深圳地区无偿献血人群因血液筛查检测 HBsAg 或抗-HCV 呈阳性反应,在规定的条件下允许其再次招回重新检测,以确定是否恢复其献血资格并重新归队献血的检测模式。方法对深圳市2007年10月至2013年12月期间无偿献血人群捐血后 HBsAg、抗-HCV 初筛反应性人员,且符合我中心制定的再次招回重新检测的献血人群进行分析研究,对无偿献血者归队模式的可行性进行探讨。结果2007~2013年期间共计415759人次,HBsAg 检测阳性2506例,抗-HCV 检测阳性1357例,阳性率分别为0.60%和0.33%。笔者对符合召回条件的59例 HBsAg 和16例抗-HCV 阳性反应的多次献血者启动了归队检测的召回流程,HBsAg、抗-HCV 项目分别有31例和9例成功完成检测流程检测项。其中29例曾经 HBsAg 呈阳性反应的献血者重新恢复献血资格,2例因后续检测不合格被屏蔽献血资格,而9例曾经抗-HCV 阳性反应而召回献血者全部恢复其献血资格。结论在现有检测模式下,血液筛查的检测技术手段很难避免因试剂、设备、人员操作等原因造成假阳性反应的发生。为了保护无偿献血人群的献血资格,必须建立一套科学、合理并具有实际操作性的献血者归队检测模式,以保护有限的无偿献血资源。
目的:探討深圳地區無償獻血人群因血液篩查檢測 HBsAg 或抗-HCV 呈暘性反應,在規定的條件下允許其再次招迴重新檢測,以確定是否恢複其獻血資格併重新歸隊獻血的檢測模式。方法對深圳市2007年10月至2013年12月期間無償獻血人群捐血後 HBsAg、抗-HCV 初篩反應性人員,且符閤我中心製定的再次招迴重新檢測的獻血人群進行分析研究,對無償獻血者歸隊模式的可行性進行探討。結果2007~2013年期間共計415759人次,HBsAg 檢測暘性2506例,抗-HCV 檢測暘性1357例,暘性率分彆為0.60%和0.33%。筆者對符閤召迴條件的59例 HBsAg 和16例抗-HCV 暘性反應的多次獻血者啟動瞭歸隊檢測的召迴流程,HBsAg、抗-HCV 項目分彆有31例和9例成功完成檢測流程檢測項。其中29例曾經 HBsAg 呈暘性反應的獻血者重新恢複獻血資格,2例因後續檢測不閤格被屏蔽獻血資格,而9例曾經抗-HCV 暘性反應而召迴獻血者全部恢複其獻血資格。結論在現有檢測模式下,血液篩查的檢測技術手段很難避免因試劑、設備、人員操作等原因造成假暘性反應的髮生。為瞭保護無償獻血人群的獻血資格,必鬚建立一套科學、閤理併具有實際操作性的獻血者歸隊檢測模式,以保護有限的無償獻血資源。
목적:탐토심수지구무상헌혈인군인혈액사사검측 HBsAg 혹항-HCV 정양성반응,재규정적조건하윤허기재차초회중신검측,이학정시부회복기헌혈자격병중신귀대헌혈적검측모식。방법대심수시2007년10월지2013년12월기간무상헌혈인군연혈후 HBsAg、항-HCV 초사반응성인원,차부합아중심제정적재차초회중신검측적헌혈인군진행분석연구,대무상헌혈자귀대모식적가행성진행탐토。결과2007~2013년기간공계415759인차,HBsAg 검측양성2506례,항-HCV 검측양성1357례,양성솔분별위0.60%화0.33%。필자대부합소회조건적59례 HBsAg 화16례항-HCV 양성반응적다차헌혈자계동료귀대검측적소회류정,HBsAg、항-HCV 항목분별유31례화9례성공완성검측류정검측항。기중29례증경 HBsAg 정양성반응적헌혈자중신회복헌혈자격,2례인후속검측불합격피병폐헌혈자격,이9례증경항-HCV 양성반응이소회헌혈자전부회복기헌혈자격。결론재현유검측모식하,혈액사사적검측기술수단흔난피면인시제、설비、인원조작등원인조성가양성반응적발생。위료보호무상헌혈인군적헌혈자격,필수건립일투과학、합리병구유실제조작성적헌혈자귀대검측모식,이보호유한적무상헌혈자원。
Objective To investigate the detection mode for those unpaid blood donors screening as positive HBsAg+ and/or positive anti-HCV could be permitted to recall again for re-detection under the regulation condition in order to determine whether or not regain their qualifications of donating blood and rejoin the blood donation again.Methods The unpaid blood donors preliminari-ly screening as positive HBsAg and/or positive anti-HCV in Shenzhen from Otcober 2007 to December 2013 and conforming to the rules for recalling to re-detection formulated by our center were analyzed and researched for conducting the feasibility discussion on the rejoin mode of unpaid blood donors.Results A total of 415 759 case-times of blood donation were conducted during 2007 ~2013.Among them,2 506 cases(0.60%)and 1 357 cases(0.33%)were screened as positive HBsAg or positive anti-HCV,respec-tively.The recall process of rejoin re-detection was initiated in 59 positive HBsAg donors and 16 positive anti-HCV donors with many times of blood donation.But only 31 positive HBsAg donors and 9 positive anti-HCV donors successfully completed the detec-tion items of re-detection process.Among them 29 positive HBsAg donor regained the qualifications of donating blood and 2 cases were shielded for the blood donation qualification due to unqualification in the following detection.All of the 9 recalled donators with positive anti-HCV regained the blood donation qualification.Conclusion Under present detection mode,the detection tech-nique of blood screening is hard to avoid the occurrence of false positive results caused by the reagents,instruments and personnel operating.In order to protect the donation qualifications of the unpaid blood donators,a set of scientific,reasonable and practical re-detection mode for rejoin of the blood donators should be established for protecting the limited blood donation resource.