CAJ | 학술논문

目的：评估胱抑素 C 与具有代谢综合征无症状冠状动脉疾病的存在和严重程度的相关性。方法对201例肾功能正常具有代谢综合征而无症状的患者进行冠状动脉造影，并对血清胱抑素 C 和动脉硬化症（ACS）其他风险因子进行检测。结果胱抑素 C 在具有代谢综合征无症状冠状动脉疾病患者中明显高于无冠状动脉疾病患者的，并越严重胱抑素 C 相对越高，且与动脉硬化症其他风险因子成独立相关。结论胱抑素 C 可作为肾功能正常的有代谢综合征的无症状冠状动脉疾病的诊断和严重性的指标。
목적：평고광억소 C 여구유대사종합정무증상관상동맥질병적존재화엄중정도적상관성。방법대201례신공능정상구유대사종합정이무증상적환자진행관상동맥조영，병대혈청광억소 C 화동맥경화증（ACS）기타풍험인자진행검측。결과광억소 C 재구유대사종합정무증상관상동맥질병환자중명현고우무관상동맥질병환자적，병월엄중광억소 C 상대월고，차여동맥경화증기타풍험인자성독립상관。결론광억소 C 가작위신공능정상적유대사종합정적무증상관상동맥질병적진단화엄중성적지표。
Objective To evaluate the relation between cystatin C and the presence and severity of asymptomatic coronary artery disease in metabolic syndrome(MetS).Methods A total of 201 asymptomatic MetS patients with normal renal function were per-formed the coronary angiograph and the detection of serum Cystatin C level and other risk factors for atherosclerosis.Results Ser-um cystatin C level in the MetS patients with asymptomatic coronary artery disease were significantly higher than those in the pa-tients without coronary artery disease,moreover the more severe of the disease,the higher the cyctatin C,which was independently associated with other risk factors for atherosclerosis.Conclusion Serum cystatin C level can been used as the index for the presence and severity of asymptomatic coronary artery disease in Mets with normal kidney function.