国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
23期
3200-3201
,共2页
儿童%低淋巴细胞血症%细胞因子%高敏 C 反应蛋白%炎症
兒童%低淋巴細胞血癥%細胞因子%高敏 C 反應蛋白%炎癥
인동%저림파세포혈증%세포인자%고민 C 반응단백%염증
children%low absolute lymphocyte count%cytokine%high sensitive C reactive protein%inflammation
目的：研究儿童低淋巴细胞血症患者的细胞因子水平。方法56例3～14岁低淋巴细胞血症儿童作为患者组，20例健康体检儿童作为对照组。用酶联免疫吸附试验（ELISA）测定血清细胞因子白细胞介素（IL）-1、IL-6、IL-8和肿瘤坏死因子（TNF）-α水平，AU640全自动生化分析仪测定高敏 C 反应蛋白（hs-CRP）水平。结果患者组的 IL-1、IL-6、IL-8和 TNF-α的水平分别为（0.096±0.012）ng／mL、（0.118±0.026）ng／mL、（0.388±0.069）ng／mL 和（1.256±0.245）ng／mL，与对照组相比差异无统计学意义（P ＞0.05）；患者组 CRP 水平为（5.7±2.8）mg／L，对照组 hs-CRP 水平为（4.8±2.6）mg／L，两者比较差异无统计学意义（P ＞0.05）。结论儿童低淋巴细胞血症患者的炎症因子并不增高，可能与其他因素有关，积极使用中药治疗有利于疾病的恢复。
目的：研究兒童低淋巴細胞血癥患者的細胞因子水平。方法56例3～14歲低淋巴細胞血癥兒童作為患者組，20例健康體檢兒童作為對照組。用酶聯免疫吸附試驗（ELISA）測定血清細胞因子白細胞介素（IL）-1、IL-6、IL-8和腫瘤壞死因子（TNF）-α水平，AU640全自動生化分析儀測定高敏 C 反應蛋白（hs-CRP）水平。結果患者組的 IL-1、IL-6、IL-8和 TNF-α的水平分彆為（0.096±0.012）ng／mL、（0.118±0.026）ng／mL、（0.388±0.069）ng／mL 和（1.256±0.245）ng／mL，與對照組相比差異無統計學意義（P ＞0.05）；患者組 CRP 水平為（5.7±2.8）mg／L，對照組 hs-CRP 水平為（4.8±2.6）mg／L，兩者比較差異無統計學意義（P ＞0.05）。結論兒童低淋巴細胞血癥患者的炎癥因子併不增高，可能與其他因素有關，積極使用中藥治療有利于疾病的恢複。
목적：연구인동저림파세포혈증환자적세포인자수평。방법56례3～14세저림파세포혈증인동작위환자조，20례건강체검인동작위대조조。용매련면역흡부시험（ELISA）측정혈청세포인자백세포개소（IL）-1、IL-6、IL-8화종류배사인자（TNF）-α수평，AU640전자동생화분석의측정고민 C 반응단백（hs-CRP）수평。결과환자조적 IL-1、IL-6、IL-8화 TNF-α적수평분별위（0.096±0.012）ng／mL、（0.118±0.026）ng／mL、（0.388±0.069）ng／mL 화（1.256±0.245）ng／mL，여대조조상비차이무통계학의의（P ＞0.05）；환자조 CRP 수평위（5.7±2.8）mg／L，대조조 hs-CRP 수평위（4.8±2.6）mg／L，량자비교차이무통계학의의（P ＞0.05）。결론인동저림파세포혈증환자적염증인자병불증고，가능여기타인소유관，적겁사용중약치료유리우질병적회복。
Objective To investigate the levels of inflammatory cytokines in children with low absolute lymphocyte count (ALC).Methods 56 patients with low ALC as the patients group and 20 children with healthy physical examination as the control group were enrolled.Several inflammatory cytokines,namely IL-1,IL-6,IL-8 and TNF-βwere measured with enzyme linked immu-nosorbent assay(ELISA)kits.High sensitive C reactive protein(Hs-CRP)was measured by the immunoturbidimetry(ITM)kit with the automatic biochemical analyzer.Results The concentrations of IL-1,IL-6,IL-8 and TNF-βin the patients were(0.096±0.012) ng/mL,(0.118±0.026)ng/mL,(0.388 ±0.069)ng/mL and(1.256 ±0.245 )ng/mL respectively,which had no statistical differ-ences as compared with the control group(P >0.05);the concentration of HsCRP in the patients group was(5.7±2.8)mg/L,while which in the control group was(4.8±2.6)mg/L,showing no statistically significant difference between them(P >0.05).Conclusion The levels of the cytokines in low ALC patients are not increased,which may be related with the other factors.Actively using tra-ditional Chinese medicine treatment is beneficial to the recovery of disease.
