CAJ | 학술논문

目的：分析吸烟对 PCI 术前男性冠状动脉心脏病（CHD）患者血脂的影响。方法随机抽取124例实施经皮冠状动脉治疗术（PCI）的男性 CHD 患者病例资料，分为吸烟组（88例）和非吸烟组（36例）。对年龄、既往病史、三酰甘油（TG）、总胆固醇（CHOL）、高密度脂蛋白（HDL）和低密度脂蛋白（LDL）等血脂进行回顾性调查研究。结果吸烟组的 LDL 为（3.1±1.34） mmol／L 高于非吸烟组[（2.5±0.95）mmol／L]，比较差异有统计学意义（P ＜0.05）；TG[（2.5±1.49）mmol／L]、HDL[（0.99±0.29）mmol／L]、LDL[（3.6±1.13）mmol／L]参数水平 CHOL（≥4.5 mmol／L 组较 CHOL＜4.5 mmol／L 组 TG[（1.8±1.23） mmol／L]、HDL[（0.88±0.20）mmol／L]、LDL[（2.20±0.69）mmol／L]组高，差异有统计学意义（P ＜0.05）；经过 Spearman 分析，发现血管病变数和 CHOL，LDL 水平呈正相关，同时吸烟程度和 LDLA 呈负相关。结论吸烟及 CHOL、LDL 水平与男性 CHD有密切关系，且吸烟可影响血脂代谢，可增加其患 CHD 的危险性。
목적：분석흡연대 PCI 술전남성관상동맥심장병（CHD）환자혈지적영향。방법수궤추취124례실시경피관상동맥치료술（PCI）적남성 CHD 환자병례자료，분위흡연조（88례）화비흡연조（36례）。대년령、기왕병사、삼선감유（TG）、총담고순（CHOL）、고밀도지단백（HDL）화저밀도지단백（LDL）등혈지진행회고성조사연구。결과흡연조적 LDL 위（3.1±1.34） mmol／L 고우비흡연조[（2.5±0.95）mmol／L]，비교차이유통계학의의（P ＜0.05）；TG[（2.5±1.49）mmol／L]、HDL[（0.99±0.29）mmol／L]、LDL[（3.6±1.13）mmol／L]삼수수평 CHOL（≥4.5 mmol／L 조교 CHOL＜4.5 mmol／L 조 TG[（1.8±1.23） mmol／L]、HDL[（0.88±0.20）mmol／L]、LDL[（2.20±0.69）mmol／L]조고，차이유통계학의의（P ＜0.05）；경과 Spearman 분석，발현혈관병변수화 CHOL，LDL 수평정정상관，동시흡연정도화 LDLA 정부상관。결론흡연급 CHOL、LDL 수평여남성 CHD유밀절관계，차흡연가영향혈지대사，가증가기환 CHD 적위험성。
Objective To analyze the effect of smoking on blood lipid before percutaneous coronary intervention(PCI)in male coronary heart disease(CHD).Methods The clinical data in 124 cases of CHD with PCI were randomly extracted and divided into the smoking group (n = 88 )and the non-smoking group (n = 36 ).The age,past disease history,triglycerides (TG),cholesterol (CHOL),low density lipoprotein(LDL)and high density lipoprotein(HDL)were retrospectively investigated.Results The LDL level of the smoking group was(3.1±1.34)mmol/L,which was significantly higher than(2.5 ±0.95)mmol/L in the non-smoking group with statistical difference between them(P <0.05);the level of TG,HDL and LDL in the CHOL≥4.5 mmol/L group were (2.5±1.49)mmol/L,(0.99±0.29)mmol/L and(3.6 ±1.13)mmol/L respectively,which were hither than(1.8 ±1.23)mmol/L, (0.88±0.20)mmol/L and(2.2±0.69)mmol/L in the CHOL≤4.5 mmol/L group respectively,the differences among them had statistical significance(P <0.05 );the Sperman analysis found that there was a positive correlation between the level of vascular change with CHOL and LDL,at the same time the smoking level was negatively correlated with LDLA.Conclusion Smoking, CHOL and LDL have a close relationship with the male coronary heart disease.Moreover,smoking can affect the lipid metabolism and probably increase the risk of coronary heart disease.