CAJ | 학술논문

目的：探讨可逆性后部白质脑病的常见病因、发病机制、临床表现、诊断及治疗措施。方法对1例产褥期可逆性后部白质脑病综合征患者的诊疗经过进行分析。结果患者有中枢神经系统症状、体征，结合相关检查结果，采用脱水、营养神经、对症支持治疗，预后良好。结论可逆性后部白质脑病综合征是一种由多种原因引起的以神经系统异常为主要表现的临床综合征。常见的病因有恶性高血压、妊娠子痫、各类严重肾脏疾病、免疫抑制剂及细胞毒药物、自身免疫病的治疗等。急性或亚急性起病，临床表现多种多样，常见的有头痛、痫性发作、视觉障碍、意识障碍及精神异常等。临床诊断主要依据其典型的影像学改变，大多数影像学改变为可逆性，预后良好。
목적：탐토가역성후부백질뇌병적상견병인、발병궤제、림상표현、진단급치료조시。방법대1례산욕기가역성후부백질뇌병종합정환자적진료경과진행분석。결과환자유중추신경계통증상、체정，결합상관검사결과，채용탈수、영양신경、대증지지치료，예후량호。결론가역성후부백질뇌병종합정시일충유다충원인인기적이신경계통이상위주요표현적림상종합정。상견적병인유악성고혈압、임신자간、각류엄중신장질병、면역억제제급세포독약물、자신면역병적치료등。급성혹아급성기병，림상표현다충다양，상견적유두통、간성발작、시각장애、의식장애급정신이상등。림상진단주요의거기전형적영상학개변，대다수영상학개변위가역성，예후량호。
Objective To investigate the common etiology ,mechanism ,clinical manifestation ,diagnosis and therapeutic options of the posterior reversible encephalopathy syndrome (PRES).Methods One PRES patient in puerperium with an onset of neurological manifestation was retrospectively reviewed.Results The patient with CNS symptoms and signs has good prog‐nosis after dehydration therapy.Conclusion PRES is a clinical syndrome caused by many reasons ,its main clinical manifesta‐tion is abnormal CNS.The common etiology includes malignant hypertension ,eclampsia ,all kinds of serious kidney disease , immunosuppressive drugs ,cytotoxic drugs ,and the treatment of autoimmune diseases and so on.Its form of onset is acute or subacute.It is varied from clinical manifestation.And the most common are headache ,seizures ,visual impairment ,conscious impairment and insanity.Clinical diagnosis is mainly based on the typical radiographic changes.Most imaging changes are re‐versible and can be disappear after 2 weeks or longer.It has a good prognosis after treatment.