CAJ | 학술논문

目的：探讨Vogt‐小柳原田综合征的发病机制、临床表现、诊断及治疗措施。方法对1例以中枢神经系统表现为首发症状的小柳原田综合症患者的诊疗经过进行分析。结果患者具有葡萄膜炎及中枢神经系统症状、体征，结合相关检查结果，采用激素治疗，预后良好。结论 Vogt‐小柳原田综合征是一个累计多个系统的免疫性疾病，临床表现多样，误诊漏诊率高，中枢神经系统表现与脑膜脑炎相似。采用视力、眼底检查、荧光素眼底血管造影（FFA ）等有助于早期诊断。应尽早行激素治疗以缩短病程，改善预后，减少并发症的发生。
목적：탐토Vogt‐소류원전종합정적발병궤제、림상표현、진단급치료조시。방법대1례이중추신경계통표현위수발증상적소류원전종합증환자적진료경과진행분석。결과환자구유포도막염급중추신경계통증상、체정，결합상관검사결과，채용격소치료，예후량호。결론 Vogt‐소류원전종합정시일개루계다개계통적면역성질병，림상표현다양，오진루진솔고，중추신경계통표현여뇌막뇌염상사。채용시력、안저검사、형광소안저혈관조영（FFA ）등유조우조기진단。응진조행격소치료이축단병정，개선예후，감소병발증적발생。
Objective To investigate the mechanism ,clinical manifestation ,diagnosis and therapeutic options of the Vogt‐Koyanagi‐Harada’s syndrome(VKHS).Methods One VKHS patient with an onset of neurological manifestation was retro‐spectively reviewed.Results this patient with uveitis and extraocular symptoms and signs ,has good prognosis after hormone therapy.Conclusion VKHS is an autoimmune inflammatory disease involving various systems.The clinical manifestations are variable and the misdiagnosis rate is high.Its neurological manifestation is similar to meningoencephalitis. Visual test ,ophthal‐moscopic examination and FFA will help in early diagnosis. Prompt initiation of hormone therapy is effectively to shorten the course ,to improve prognosis and diminish the complications.