CAJ | 학술논문

目的：观察复方樟柳碱注射液治疗缺血性视神经病变的临床疗效。方法选择76例缺血性视神经病变患者，按照随机数字对照表法平均分为两组，研究组38例（49眼），对照组38例（45眼）。两组患者均给予复方血栓通、复方丹参等传统的扩张血管的药物治疗，同时，配以维生素B1、B12、肌苷、三磷酸腺苷片、泼尼松等进行治疗。研究组在常规治疗的基础上，加用复方樟柳碱注射液于患侧颞浅动脉旁注射治疗，2毫升/次，1次/天，2周为一个疗程。一个疗程治疗结束后观察两组患者视力、视野的变化，比较两组的临床疗效。结果经治疗两组患者的视力及视野均得到明显的改善，研究组视力、视野的治疗总有效率分别为93.88%、91.84%，均明显高于对照组的86.67%、80.00%（P＜0.05）。两组患者均未发生严重不良反应。结论复方樟柳碱注射液治疗缺血性视神经病变临床疗效确切，能够改善患者的视力水平及视野损伤情况，提高生活质量，值得临床推广。
목적：관찰복방장류감주사액치료결혈성시신경병변적림상료효。방법선택76례결혈성시신경병변환자，안조수궤수자대조표법평균분위량조，연구조38례（49안），대조조38례（45안）。량조환자균급여복방혈전통、복방단삼등전통적확장혈관적약물치료，동시，배이유생소B1、B12、기감、삼린산선감편、발니송등진행치료。연구조재상규치료적기출상，가용복방장류감주사액우환측섭천동맥방주사치료，2호승/차，1차/천，2주위일개료정。일개료정치료결속후관찰량조환자시력、시야적변화，비교량조적림상료효。결과경치료량조환자적시력급시야균득도명현적개선，연구조시력、시야적치료총유효솔분별위93.88%、91.84%，균명현고우대조조적86.67%、80.00%（P＜0.05）。량조환자균미발생엄중불량반응。결론복방장류감주사액치료결혈성시신경병변림상료효학절，능구개선환자적시력수평급시야손상정황，제고생활질량，치득림상추엄。
Objective To observe the clinical curative effect of compound anisodine hydrobromide injection treatment of ischemic optic neuropathy.Methods 76 patients with ischemic opticneuropathy were divided into two groups according to the random number table method, study group 38 cases (49 eyes), 38 cases in the control group (45 eyes). Two groups were given fufang xueshuantong, salvia and other traditional vascular dilation drug treatment, at the same time, with treatment withvitamin B1, B12, inosine, adenosine triphosphate, prednisone, etc. On the basis of conventional therapy, the study group plus compound anisodine hydrobromide injection on ipsilateral para temporal superifcial artery injection therapy, once a day, each 2 mL, two week for a course of treatment. The clinical efifcacy of the two groups were compared.Results The visual acuity and visual ifeld in two groups of patients were improved obviously, the total effective rates of study were 93.88%and 91.84%, were signiifcantly higher than 86.67% and 80% in control group (P<0.05). Patients in the two groups were no serious adverse reactions.Conclusion Compound anisodine hydrobromide injection in the treatment of ischemic optic neuropathyexact has good clinical curative effect, can improve visual acuity and visual ifeld damage of patients, improve the quality of life, worthy of clinical application.