CAJ | 학술논문

手术是治疗肝癌的主要手段，但在我国，肝癌患者往往合并有肝炎及肝硬化，使得肝脏储备能力显著下降，加大了患者围手术期的风险性。因此，术前肝功能储备评估对肝切除手术患者的预后起着非常重要的作用。日本对肝癌的研究在全世界范围来讲一直处于比较领先的地位，但目前日本行大肝癌切除的病例有明显下降趋势，而在我国，很多肝癌患者肿瘤都比较巨大，由于术前评估不良而进行手术导致了高死亡率和高并发症发生率以及由于术前评估系统的不完善使得原本有手术切除机会的巨大肝癌患者没有选择手术治疗而错失了机会，这些问题在国内尤为显著。因此，术前准确评估肝脏储备功能对临床选择治疗方案以及降低术后肝衰竭的发生率具有重要的意义。本文将就近年来术前肝功能储备评估的研究进展作一概述。
수술시치료간암적주요수단，단재아국，간암환자왕왕합병유간염급간경화，사득간장저비능력현저하강，가대료환자위수술기적풍험성。인차，술전간공능저비평고대간절제수술환자적예후기착비상중요적작용。일본대간암적연구재전세계범위래강일직처우비교령선적지위，단목전일본행대간암절제적병례유명현하강추세，이재아국，흔다간암환자종류도비교거대，유우술전평고불량이진행수술도치료고사망솔화고병발증발생솔이급유우술전평고계통적불완선사득원본유수술절제궤회적거대간암환자몰유선택수술치료이착실료궤회，저사문제재국내우위현저。인차，술전준학평고간장저비공능대림상선택치료방안이급강저술후간쇠갈적발생솔구유중요적의의。본문장취근년래술전간공능저비평고적연구진전작일개술。
Liver resection is the main stone for treatment of liver cancer. In our country, patients with liver cancer are always with hepatitis and/or cirrhosis. Therefore, their liver reserve capacity may be reduced. And the risk of perioperative mortality is increased. So, preoperative liver functional reserve assessment plays an important role in the prognosis of patients who will undergo hepatic resection. The treatment modality of liver cancer in Japan is in the leading position. But the rate of major hepatectomy is reduced in the last decade. While in China, many patients with liver cancer are diagnosed in late stage. Due to preoperative assessment is not comprehensively, the surgery leads to high mortality and high incidence rate of complication. Because of the imperfect preoperative evaluation system has had the huge liver cancer resection operation opportunity not choose operation treatment and missed the opportunity, these problems become more prominent in the domestic. Therefore, the preoperative accurate evaluation of liver functional reserve for clinical therapy and reduce the incidence of postoperative liver failure has important significance. In this paper, research progress of preoperative liver function reserve assessment in recent years was summarized.