CAJ | 학술논문

目的：通过临床使用注射用细辛脑对喘息性支气管炎患儿，观察临床疗效。方法使用注射用细辛脑和氨茶碱注射液治疗喘息性支气管炎，观察其疗效，并检测痰液和血液中的特异性指标。结果治疗2周后，两组喘息性支气管炎患儿血细胞学检查提示巨噬细胞、嗜酸性粒细胞跟治疗前和治疗后比较均有明显差异（P均＜0.05），同时治疗组的CD4+T淋巴细胞、淋巴细胞和治疗前比较均有明显差异（P均＜0.05)。两组巨噬细胞、嗜酸性粒细胞、CD4+T细胞、淋巴细胞比较也提示有明显差异(P均＜0.05)。治疗后观察组和治疗组患儿肺功能均比治疗前明显改善(P均＜0.05)，治疗组的IL-5、肺功能跟观察组有明显差异(P＜0.05)。结论注射用细辛脑和氨茶碱注射液对喘息性支气管炎均有效，两组药物对比，注射用细辛脑效果比氨茶碱效果更好。在临床上，细辛脑对于喘息性呼吸道疾病的治疗效果好，经济实惠，值得临床推广。
목적：통과림상사용주사용세신뇌대천식성지기관염환인，관찰림상료효。방법사용주사용세신뇌화안다감주사액치료천식성지기관염，관찰기료효，병검측담액화혈액중적특이성지표。결과치료2주후，량조천식성지기관염환인혈세포학검사제시거서세포、기산성립세포근치료전화치료후비교균유명현차이（P균＜0.05），동시치료조적CD4+T림파세포、림파세포화치료전비교균유명현차이（P균＜0.05)。량조거서세포、기산성립세포、CD4+T세포、림파세포비교야제시유명현차이(P균＜0.05)。치료후관찰조화치료조환인폐공능균비치료전명현개선(P균＜0.05)，치료조적IL-5、폐공능근관찰조유명현차이(P＜0.05)。결론주사용세신뇌화안다감주사액대천식성지기관염균유효，량조약물대비，주사용세신뇌효과비안다감효과경호。재림상상，세신뇌대우천식성호흡도질병적치료효과호，경제실혜，치득림상추엄。
Objectiv Through clinical use in asarone injection on children with asthmatic bronchitis, observe clinical curative effect.Methods 60 cases of children with asthmatic bronchitis are selected and randomly divided into 2 groups, treatment group was given in asarone injection of 0.5 mg/kg, with 10% glucose injection diluted into 0.01% of the solution, the intravenous drip, 1 time/day; while the control group with aminophylline injection 3-5 mg/kg in 5% glucose injection, 100 mL, intravenous drip, 1 time/day. Two groups of 7 days for a period of treatment, observation of two procedures.Results 2 weeks after treatment, two groups of eosinophilic granulocytes and macrophages, comparison before and after the treatment have obvious difference (P<0.05), at the same time, the treatment group of lymphoid cells and CD4+ T cells are obvious difference compared with before treatment (P<0.05). Two groups of eosinophils, lymphocytes, macrophages, CD4+ T cells is also has the obvious difference (P<0.05). Lung function in the two groups after treatment were obviously improved than before treatment (P<0.05), the treatment group of pulmonary function, IL-5 and the control group had obvious difference (P<0.05).Conclusion For injection asarone effects on asthmatic bronchitis in children with respiratory tract is better than that of aminophylline group, clinically; asarone in asthmatic airway diseases treatment effect is good, affordable, worth clinical promotion.