中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2014年
33期
41-42
,共2页
青少年%精神分裂症%认知功能
青少年%精神分裂癥%認知功能
청소년%정신분렬증%인지공능
Adolescent mental%Schizophrenia%Cognitive function
目的：研究分析青少年精神分裂症患者治疗前后的认知功能损害情况以及抗精神病药治疗对认知功能的影响。方法对60例青少年精神分裂症诊断标准的患者于治疗前及治疗12周后采用华文认知能力量表（CCAS）、阳性与阴性症状量表（PANSS）进行评定；同时调查患者的临床特征。结果青少年精神分裂症患者治疗后患者的CCAS共组记忆、学习能力、推理能力、加工速度、空间/计算等认知功能和言语智商、操作智商以及总智商（IQ）均较治疗前有不同程度提高；治疗前后比较差异均有统计学意义（P均＜0.05)。经Pearson相关分析，治疗前后IQ的差值与PANSS总分及阳性总分差值呈正相关（P＜0.05)，而IQ差值与阴性总分及一般症状总分差值无相关性（P＞0.05)。结论青少年精神分裂症患者常常存在不同程度的认知功能损害，并与精神症状有一定的相关性，经治疗后患者的认知功能较前有所改善。
目的：研究分析青少年精神分裂癥患者治療前後的認知功能損害情況以及抗精神病藥治療對認知功能的影響。方法對60例青少年精神分裂癥診斷標準的患者于治療前及治療12週後採用華文認知能力量錶（CCAS）、暘性與陰性癥狀量錶（PANSS）進行評定；同時調查患者的臨床特徵。結果青少年精神分裂癥患者治療後患者的CCAS共組記憶、學習能力、推理能力、加工速度、空間/計算等認知功能和言語智商、操作智商以及總智商（IQ）均較治療前有不同程度提高；治療前後比較差異均有統計學意義（P均＜0.05)。經Pearson相關分析，治療前後IQ的差值與PANSS總分及暘性總分差值呈正相關（P＜0.05)，而IQ差值與陰性總分及一般癥狀總分差值無相關性（P＞0.05)。結論青少年精神分裂癥患者常常存在不同程度的認知功能損害，併與精神癥狀有一定的相關性，經治療後患者的認知功能較前有所改善。
목적：연구분석청소년정신분렬증환자치료전후적인지공능손해정황이급항정신병약치료대인지공능적영향。방법대60례청소년정신분렬증진단표준적환자우치료전급치료12주후채용화문인지능역량표（CCAS）、양성여음성증상량표（PANSS）진행평정；동시조사환자적림상특정。결과청소년정신분렬증환자치료후환자적CCAS공조기억、학습능력、추리능력、가공속도、공간/계산등인지공능화언어지상、조작지상이급총지상（IQ）균교치료전유불동정도제고；치료전후비교차이균유통계학의의（P균＜0.05)。경Pearson상관분석，치료전후IQ적차치여PANSS총분급양성총분차치정정상관（P＜0.05)，이IQ차치여음성총분급일반증상총분차치무상관성（P＞0.05)。결론청소년정신분렬증환자상상존재불동정도적인지공능손해，병여정신증상유일정적상관성，경치료후환자적인지공능교전유소개선。
Objective To explore the characteristics of cognition function impairment and the treatment inlfuence on cognitive function in patients with ifrst-episode of the adolescent schizophrenia.Method 60 adolescent schizophrenic patients meeting with Chinese classiifcation of mental disorders 3nd version were evaluated with Chinese cognitive ability scale (CCAS) and positive and negative syndrome scale (PANSS) before treatment and after 12 weeks treatment. Meanwhile the clinical features were investigated in these patients.Results Adolescent mental treatment of schizophrenic patients after CCAS were memory, learning ability, reasoning ability, processing speed, cognitive functions such as spatial / calculation and VIQ, PIQ and FIQ (IQ) were observed before the treatment, there are different levels; before and after treatment the difference had statistical signiifcance (P<0.05). The Pearson correlation analysis difference between before and after treatment IQ and PANSS total scores and positive score difference was positively correlated (P<0.05). While the IQ difference and negative score and symptom score difference no correlation (P>0.05).Conclusion Adolescent schizophrenia patients often have different levels of cognitive impairment, and there is a certain correlation with psychiatric symptoms, after treatment the cognitive function of patients signiifcantly improved.
