中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2014年
33期
39-40
,共2页
酮症酸中毒%高渗%老年%急救效果
酮癥痠中毒%高滲%老年%急救效果
동증산중독%고삼%노년%급구효과
Ketoacidosis%Hypertonic state%Elderly%Emergency effect
目的:探讨糖尿病并发酮症酸中毒的救治方法。方法选取2010年1月至2014年5月发生糖尿病酮症酸中毒患者共65例,根据血钠浓度及血渗透压分为2组。A组:合并血钠浓度>150 mmol/L,血渗透压>330 mOsm/L,共31例;B组:血钠浓度<145 mmol/L,血渗透压<330 mOsm/L,共34例。两组均进行大量补液及小剂量胰岛素治疗,联合胃肠补液,当血糖降至13.9 mmol/L改为5%葡萄糖液。结果65例患者总的治疗效果为有效59例(有效率90.7%),死亡6例(9.3%),其中6例年龄均>65岁,且合并心功能不全,肾功能障碍等基础疾病。A组患者治疗效果为有效26例(83.9%),死亡5例(16.1%)。B组患者治疗效果为有33例(97.1%),死亡1例(2.9%)。结论及时对糖尿病酮症酸中毒患者进行正确的抢救能有效地降低酮症酸中毒的病死率。其中糖尿病酮症酸中毒合并高渗状态,以及老年患者预后不佳,是导致死亡的重要因素。
目的:探討糖尿病併髮酮癥痠中毒的救治方法。方法選取2010年1月至2014年5月髮生糖尿病酮癥痠中毒患者共65例,根據血鈉濃度及血滲透壓分為2組。A組:閤併血鈉濃度>150 mmol/L,血滲透壓>330 mOsm/L,共31例;B組:血鈉濃度<145 mmol/L,血滲透壓<330 mOsm/L,共34例。兩組均進行大量補液及小劑量胰島素治療,聯閤胃腸補液,噹血糖降至13.9 mmol/L改為5%葡萄糖液。結果65例患者總的治療效果為有效59例(有效率90.7%),死亡6例(9.3%),其中6例年齡均>65歲,且閤併心功能不全,腎功能障礙等基礎疾病。A組患者治療效果為有效26例(83.9%),死亡5例(16.1%)。B組患者治療效果為有33例(97.1%),死亡1例(2.9%)。結論及時對糖尿病酮癥痠中毒患者進行正確的搶救能有效地降低酮癥痠中毒的病死率。其中糖尿病酮癥痠中毒閤併高滲狀態,以及老年患者預後不佳,是導緻死亡的重要因素。
목적:탐토당뇨병병발동증산중독적구치방법。방법선취2010년1월지2014년5월발생당뇨병동증산중독환자공65례,근거혈납농도급혈삼투압분위2조。A조:합병혈납농도>150 mmol/L,혈삼투압>330 mOsm/L,공31례;B조:혈납농도<145 mmol/L,혈삼투압<330 mOsm/L,공34례。량조균진행대량보액급소제량이도소치료,연합위장보액,당혈당강지13.9 mmol/L개위5%포도당액。결과65례환자총적치료효과위유효59례(유효솔90.7%),사망6례(9.3%),기중6례년령균>65세,차합병심공능불전,신공능장애등기출질병。A조환자치료효과위유효26례(83.9%),사망5례(16.1%)。B조환자치료효과위유33례(97.1%),사망1례(2.9%)。결론급시대당뇨병동증산중독환자진행정학적창구능유효지강저동증산중독적병사솔。기중당뇨병동증산중독합병고삼상태,이급노년환자예후불가,시도치사망적중요인소。
Objective To study the emergency method of diabetes mellitus ketoacidosis.Methods 65 patients with diabetes mellitus ketoacidosis who were treated with a large number of lfuid and small doses of insulin, gastrointestinal lfuid in our hospital from January 2010 to May 2014. When blood glucose descends to 13.9 mmol/L, replace with 5% glucose solution. According to the serum sodium concentration and plasma osmotic pressure, the patients were divided into group A and group B. 31 cases in group A with blood serum concentration>150 mmol/L and blood osmotic pressure>330 mOsm /L; while 34 cases in group B with blood serum concentration<145 mmol/L and blood osmotic pressure<330 mOsm/L.Results The therapeutic effect of 65 cases with total effective in 59 cases(total efifciency 90.7%), there were 6 cases of death (total death rate 9.3%), with aged >65 years in average and background dieses such as incomplete function of heart and kidney. The therapeutic effect in group A was 26 cases(efifciency 83.9%) and death rate was 16.1%; while effective 33 cases in group B (efifciency 97.1%) and death rate 2.9%.Conclusion Timely and effective rescue of patients with diabetic ketoacidosis could effectively reduce the mortality of diabetic ketoacidosis. Diabetes mellitus ketoacidosis complicated with hyperglycemic hyperosmolar state and gerontism were important factors leading to death, the prognosis were worse.