中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
49期
8026-8030
,共5页
实验动物%组织工程%脊髓损伤%诱发电位%体感诱发电位%运动诱发电位%动物模型
實驗動物%組織工程%脊髓損傷%誘髮電位%體感誘髮電位%運動誘髮電位%動物模型
실험동물%조직공정%척수손상%유발전위%체감유발전위%운동유발전위%동물모형
spinal cord injuries%evoked potentials%evoked potentials,motor%evoked potentials,somatosensory
背景：随着工业社会的发展和交通的发达，脊髓损伤的发病率也逐年升高。脊髓损伤的辅助检查手段除了影像学以外，神经电生理技术的应用也越来越广泛。其中诱发电位因其准确率高、操作简便应用较多。目的：综述躯体感觉诱发电位及运动诱发电位在兔脊髓损伤中的应用情况。方法：通过检索中国知网、PubMed数据库，输入“脊髓损伤，诱发电位，动物模型，Spinal cord injury，evoked potential，animal model”等关键词进行检索，最终纳入文章33篇进入结果分析。结果与结论：详细阐述了体感诱发电位与运动诱发电位在动物实验中的操作方法、波形分析、应用价值、影响因素及诱发电位与动物预后功能评价。其中体感诱发电位是反应脊髓后索功能的很好指标，操作简便，对检测患者感觉功能的变化有很好的指导作用。运动诱发电位能为各种脊髓疾病提供敏感而精确的诊断，尤其在患者治疗和康复期间可作为重要的评估手段。而两者连用效果更精确。
揹景：隨著工業社會的髮展和交通的髮達，脊髓損傷的髮病率也逐年升高。脊髓損傷的輔助檢查手段除瞭影像學以外，神經電生理技術的應用也越來越廣汎。其中誘髮電位因其準確率高、操作簡便應用較多。目的：綜述軀體感覺誘髮電位及運動誘髮電位在兔脊髓損傷中的應用情況。方法：通過檢索中國知網、PubMed數據庫，輸入“脊髓損傷，誘髮電位，動物模型，Spinal cord injury，evoked potential，animal model”等關鍵詞進行檢索，最終納入文章33篇進入結果分析。結果與結論：詳細闡述瞭體感誘髮電位與運動誘髮電位在動物實驗中的操作方法、波形分析、應用價值、影響因素及誘髮電位與動物預後功能評價。其中體感誘髮電位是反應脊髓後索功能的很好指標，操作簡便，對檢測患者感覺功能的變化有很好的指導作用。運動誘髮電位能為各種脊髓疾病提供敏感而精確的診斷，尤其在患者治療和康複期間可作為重要的評估手段。而兩者連用效果更精確。
배경：수착공업사회적발전화교통적발체，척수손상적발병솔야축년승고。척수손상적보조검사수단제료영상학이외，신경전생리기술적응용야월래월엄범。기중유발전위인기준학솔고、조작간편응용교다。목적：종술구체감각유발전위급운동유발전위재토척수손상중적응용정황。방법：통과검색중국지망、PubMed수거고，수입“척수손상，유발전위，동물모형，Spinal cord injury，evoked potential，animal model”등관건사진행검색，최종납입문장33편진입결과분석。결과여결론：상세천술료체감유발전위여운동유발전위재동물실험중적조작방법、파형분석、응용개치、영향인소급유발전위여동물예후공능평개。기중체감유발전위시반응척수후색공능적흔호지표，조작간편，대검측환자감각공능적변화유흔호적지도작용。운동유발전위능위각충척수질병제공민감이정학적진단，우기재환자치료화강복기간가작위중요적평고수단。이량자련용효과경정학。
BACKGROUND:With the development of industrial society and traffic, the incidence of spinal cord injury has gradualy increased. In addition to radiological laboratory examinations, the neurophysiological test also becomes an effective way of auxiliary examination. Due to the high accuracy and easy operating, neurophysiological test is widely used and the evoked potentials play a role in this project. OBJECTIVE:To summarize the application of somatosensory evoked potentials and motor evoked potentials in rabbits of spinal cord injury. METHODS:A computer-based online research of CNKI and PubMed databases was performed with the key words of “spinal cord injury; evoked potentials; animal models” in Chinese and English. Finaly 33 articles were included in the analysis according to the inclusion and exclusion criteria. RESULTS AND CONCLUSION:The operational approach, waveform analysis, application value, influencing factor of somatosensory evoked potentials and motor evoked potentials were determined in details, the correlation between evoked potentials and prognosis assessment in animals was also detected. Somatosensory evoked potentials is a good indicator for the evaluation of dorsal funiculus of spinal cord, it is easy to operate and reflects the changes of sensory functions. Motor evoked potentials can provide sensitive diagnosis of spinal cord diseases, and they wil be used as a means to assess the spinal cord injury during rehabilitation. The combination of the two can provide a more accurate result.
