CAJ | 학술논문

目的：观察血必净注射液治疗重症肺炎的临床疗效和安全性。方法：将126例重症肺炎患者分为常规组（63例）和治疗组（63例），常规组给予常规抗感染、祛痰、机械通气、对症支持治疗，治疗组在此基础上加用血必净注射液静脉滴注，14 d为一个疗程。比较2组患者临床疗效和安全性。结果：治疗组总有效率（87．30％）高于常规组（66．67％）（χ2＝7．570，P＝0．006）。治疗组较常规组缩短了机械通气时间、抗生素使用时间和住院时间（t＝7．183、6．102、7．616，P均＜0．001），降低了60 d病死率（7．94％vs 20．63％，χ2＝4．148，P＝0．036）。2组患者均未发生与药物相关的严重不良反应。结论：在常规西药治疗的基础上加用血必净注射液治疗重症肺炎，具有一定的临床应用价值。
목적：관찰혈필정주사액치료중증폐염적림상료효화안전성。방법：장126례중증폐염환자분위상규조（63례）화치료조（63례），상규조급여상규항감염、거담、궤계통기、대증지지치료，치료조재차기출상가용혈필정주사액정맥적주，14 d위일개료정。비교2조환자림상료효화안전성。결과：치료조총유효솔（87．30％）고우상규조（66．67％）（χ2＝7．570，P＝0．006）。치료조교상규조축단료궤계통기시간、항생소사용시간화주원시간（t＝7．183、6．102、7．616，P균＜0．001），강저료60 d병사솔（7．94％vs 20．63％，χ2＝4．148，P＝0．036）。2조환자균미발생여약물상관적엄중불량반응。결론：재상규서약치료적기출상가용혈필정주사액치료중증폐염，구유일정적림상응용개치。
Aim:To observe the clinical efficacy and safety of Xuebijing injection in patients with severe pneumonia . Methods:A total of 126 patients with severe pneumonia were divided into routine group (n=63)and treatment group(n=63).Patients in the routine group were in routine therapy .Treatment of routine therapy combined with Xuebijing injection was applied in the treatment group .The clinical efficacy in the two groups were observed .Results:The effective rate was higher in treatment group than that of the routine group (87.30% vs 66.67%,χ2 =7.570,P=0.006).The mechanical ventilation time,antibiotic using time, and hospital stay shortened in treatment group (t =7.183,6.102,7.616,P <0.001).The fatality rate at 60th of treatment group was lower compared with that of routine group (7.94% vs 20.63%,χ2 =4.148,P=0.036).There were no obvious adverse reaction in two groups .Conclusion:Treatment of routine therapy combined with Xuebijing injection for severe pneumonia has certain clinical application value .