CAJ | 학술논문

目的：探讨SPECT-CT融合图像评价原发性肝癌骨转移的增益价值。方法回顾性分析临床诊断为原发性肝癌、排除其他恶性肿瘤病史且行全身骨显像及局部SPECT-CT融合图像检查的254例患者的临床资料，根据患者综合表现诊断为肿瘤骨转移和无肿瘤骨转移，以手术病理或随访结果为最终诊断标准。分别计算并比较全身骨显像、SPECT-CT融合图像诊断的灵敏度、特异度、阳性预测值、阴性预测值和正确诊断百分率。结果254例患者中确诊肿瘤骨转移111例，无肿瘤骨转移143例。SPECT-CT融合图像诊断的灵敏度（93.6%）、特异度（93.7%）、阳性预测值（99%）、阴性预测值（100%）、正确诊断百分率（93.3%）均高于全身骨扫描（42.3%、74.8%、95.7%、92.5%、56.7%）。结论评价肝癌骨转移时，SPECT-CT融合图像较全身骨显像更具有增益价值。
목적：탐토SPECT-CT융합도상평개원발성간암골전이적증익개치。방법회고성분석림상진단위원발성간암、배제기타악성종류병사차행전신골현상급국부SPECT-CT융합도상검사적254례환자적림상자료，근거환자종합표현진단위종류골전이화무종류골전이，이수술병리혹수방결과위최종진단표준。분별계산병비교전신골현상、SPECT-CT융합도상진단적령민도、특이도、양성예측치、음성예측치화정학진단백분솔。결과254례환자중학진종류골전이111례，무종류골전이143례。SPECT-CT융합도상진단적령민도（93.6%）、특이도（93.7%）、양성예측치（99%）、음성예측치（100%）、정학진단백분솔（93.3%）균고우전신골소묘（42.3%、74.8%、95.7%、92.5%、56.7%）。결론평개간암골전이시，SPECT-CT융합도상교전신골현상경구유증익개치。
ObjectiveTo investigate the incremental diagnostic value of SPECT-CT fusion imaging for bone metastases from primary liver cancer.MethodA total of 254 patients with primary liver cancer but without other malignancy, conifrmed by clinical, underwent routine whole-body bone scintigraphy and local SPECT-CT. Patients were divided into positive bone metastases group, negative bone metastases group and uncertain group according to the comprehensive manifestation. The ifnal diagnosis was conifrmed by clinical follow-up or surgical pathology. Sensitivity, speciifcity, positive predictive value, negative predictive value and diagnostic accuracy of WBBS and SPECT-CT for cases were computed and compared.ResultWithin 254 patients, 111 were diagnosed as positive bone metastases and other 143 patients were diagnosed as negative bone metastasis. Sensitivity, speciifcity, positive predictive value, negative predictive value, diagnostic accuracy of SPECT-CT for cases were 93.6%, 93.7%, 99.0%, 100.0%, 93.3%, respectively, much higher than those of WBBS (42.3%, 74.8%, 95.7%, 92.5%, 56.7%).ConclusionSPECT-CT fusion imaging provides incremental diagnostic value over routine whole-body bone scintigraphy for bone metastases from primary carcinoma of the liver.