中国医学前沿杂志（电子版）
中國醫學前沿雜誌（電子版）
중국의학전연잡지（전자판）
CHINESE JOURNAL OF THE FRONTIERS OF MEDICAL SCIENCE(ELECTRONIC VERSION)
2014年
10期
95-97
,共3页
急性胰腺炎%血清降钙素原%水平变化%临床意义
急性胰腺炎%血清降鈣素原%水平變化%臨床意義
급성이선염%혈청강개소원%수평변화%림상의의
Acute pancreatitis%Serum procalcitonin levels%Level change%Clinical signiifcance
目的：探讨急性胰腺炎患者血清降钙素原（PCT）水平变化与临床意义。方法选取本院2012年2月至2014年2月收治的急性胰腺炎患者150例，按照临床标准将其分为急性轻症胰腺炎组和急性重症胰腺炎组，每组各75例。两组患者治疗前血清PCT水平与正常值[（0.55±0.21）μg/L]进行比较，比较两组患者治疗前后血清PCT水平。结果两组患者治疗前血清PCT水平均显著高于正常值（P＜0.01），组间比较差异具有显著性（t＝12.4611，P＜0.05）；治疗1、3、7天后，急性轻症胰腺炎组患者PCT水平明显低于急性重症胰腺炎组，差异具有显著性（t＝53.1159，P＜0.01；t＝61.7751，P＜0.01；t＝92.1915，P＜0.01）。随治疗时间的延长，急性轻症胰腺炎组患者血清PCT水平逐渐降低，而急性重症胰腺炎组患者血清PCT水平一直较高，且呈逐渐升高的趋势。结论血清PCT水平反映急性胰腺炎的病情程度，可用于早期判断患者是否感染，有利于急性胰腺炎的早期预防及治疗，方法简单，准确度较高，值得临床推广应用。
目的：探討急性胰腺炎患者血清降鈣素原（PCT）水平變化與臨床意義。方法選取本院2012年2月至2014年2月收治的急性胰腺炎患者150例，按照臨床標準將其分為急性輕癥胰腺炎組和急性重癥胰腺炎組，每組各75例。兩組患者治療前血清PCT水平與正常值[（0.55±0.21）μg/L]進行比較，比較兩組患者治療前後血清PCT水平。結果兩組患者治療前血清PCT水平均顯著高于正常值（P＜0.01），組間比較差異具有顯著性（t＝12.4611，P＜0.05）；治療1、3、7天後，急性輕癥胰腺炎組患者PCT水平明顯低于急性重癥胰腺炎組，差異具有顯著性（t＝53.1159，P＜0.01；t＝61.7751，P＜0.01；t＝92.1915，P＜0.01）。隨治療時間的延長，急性輕癥胰腺炎組患者血清PCT水平逐漸降低，而急性重癥胰腺炎組患者血清PCT水平一直較高，且呈逐漸升高的趨勢。結論血清PCT水平反映急性胰腺炎的病情程度，可用于早期判斷患者是否感染，有利于急性胰腺炎的早期預防及治療，方法簡單，準確度較高，值得臨床推廣應用。
목적：탐토급성이선염환자혈청강개소원（PCT）수평변화여림상의의。방법선취본원2012년2월지2014년2월수치적급성이선염환자150례，안조림상표준장기분위급성경증이선염조화급성중증이선염조，매조각75례。량조환자치료전혈청PCT수평여정상치[（0.55±0.21）μg/L]진행비교，비교량조환자치료전후혈청PCT수평。결과량조환자치료전혈청PCT수평균현저고우정상치（P＜0.01），조간비교차이구유현저성（t＝12.4611，P＜0.05）；치료1、3、7천후，급성경증이선염조환자PCT수평명현저우급성중증이선염조，차이구유현저성（t＝53.1159，P＜0.01；t＝61.7751，P＜0.01；t＝92.1915，P＜0.01）。수치료시간적연장，급성경증이선염조환자혈청PCT수평축점강저，이급성중증이선염조환자혈청PCT수평일직교고，차정축점승고적추세。결론혈청PCT수평반영급성이선염적병정정도，가용우조기판단환자시부감염，유리우급성이선염적조기예방급치료，방법간단，준학도교고，치득림상추엄응용。
ObjectiveTo investigate serum procalcitonin (PCT) level in patients with acute pancreatitis and its clinical signiifcance.Method150 patients with acute pancreatitis were selected from February 2012 to February 2014 in our hospital. According to clinical criteria, 150 patients were divided into acute mild pancreatitis group and severe acute pancreatitis group, 75 cases in each group. Compared the serum PCT level of two groups before and after treatment.ResultBefore treatment, the PCT levels of two groups of patients were signiifcantly higher than normal level (P<0.01). Before treatment, the PCT levels of two groups of patients had signiifcant difference (t=12.4611,P<0.05). After 1, 3, 7 days acute, the PCT levels of patients in severe pancreatitis group were signiifcantly higher than those mild acute pancreatitis group (t=53.1159,P<0.01;t=61.7751,P<0.01;t=92.1915,P<0.01). With the extension of treatment time, the dynamic changes of PCT levels in two groups of patients was different, after treatment, PCT levels were decreased gradually of mild acute pancreatitis group patients, and severe acute pancreatitis group of patients with PCT levels were higher, and had the trend of gradually increasing.ConclusionSerum procalcitonin can relfect the severity of acute pancreatitis, it can be used to determine whether patients had the early infection, it is helpful for the early prevention and treatment of acute pancreatitis, this value is simple and accurate. It is worth popularizing in clinic.
