CAJ | 학술논문

恶性肿瘤是我国最常见的导致死亡的疾病。由于病因与发病机制复杂，且缺乏早期诊断的特异性指标，导致诊断和治疗滞后，病死率高。随着基础研究的发展，越来越多提示早期肿瘤存在的特异性标志物被发现，但目前的检测大多依赖于大型医院的专业实验室，耗时长，价格昂贵，给患者在时间和经济上带来诸多困难且在医疗资源匮乏地区难以推广。近期新兴的检验模式POCT发展迅猛，因其设备便携，获得结果迅速，可在社区等基层医疗机构以及经济落后地区开展，有利于人群中肿瘤标志物（ TM）的筛查。通过POCT在TM领域的应用，以期实现对肿瘤早发现、早诊断、早治疗，降低死亡率。
악성종류시아국최상견적도치사망적질병。유우병인여발병궤제복잡，차결핍조기진단적특이성지표，도치진단화치료체후，병사솔고。수착기출연구적발전，월래월다제시조기종류존재적특이성표지물피발현，단목전적검측대다의뢰우대형의원적전업실험실，모시장，개격앙귀，급환자재시간화경제상대래제다곤난차재의료자원궤핍지구난이추엄。근기신흥적검험모식POCT발전신맹，인기설비편휴，획득결과신속，가재사구등기층의료궤구이급경제락후지구개전，유리우인군중종류표지물（ TM）적사사。통과POCT재TM영역적응용，이기실현대종류조발현、조진단、조치료，강저사망솔。
Malignant tumors are the most common lethal diseases in China.Because of complexity of etiology and pathogenesis , and the lack of specific markers for early diagnosis , delayed diagnosis and treatment of cancer , the fatality rate is high.With the development of basic research , more and more early specific markers were found , but the current detection mostly depend on the professional laboratories , time-consuming , high price and have a number of inconveniences to patients on time and money.Meanwhile , it′s difficult to extend to zoon of medicine resources deficient.Recently, point-of-care testing (POCT) has been rapidly developed , because of its portability , getting results quickly , can be operated in basic medical units and economic backward areas , so it′s benefit to cancer screening in human.By the application in tumor markers, POCT can be done for the cancer early detection , early diagnosis and early treatment , so then cuts the death rate.