实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
PRACTICAL JOURNAL OF CARDIAC CEREBRAL PNEUMAL AND VASCULAR DISEASE
2014年
11期
23-25
,共3页
徐芸%陈先辉%邓香君%李玫%黄鸿%景孟娟%李思琴%黄国珍%刘丽%田黎
徐蕓%陳先輝%鄧香君%李玫%黃鴻%景孟娟%李思琴%黃國珍%劉麗%田黎
서예%진선휘%산향군%리매%황홍%경맹연%리사금%황국진%류려%전려
卒中%疲劳%白细胞介素-1β%护理
卒中%疲勞%白細胞介素-1β%護理
졸중%피로%백세포개소-1β%호리
Stroke%Fatigue%Interleukin -1β%Nursing care
目的:探讨脑卒中后疲劳( PSF)患者血清白介素-1β( IL-1β)水平变化及早期护理干预效果,为PSF的防治提供参考。方法选取2013年12月—2014年6月我院收治的缺血性脑卒中患者105例,随机分为对照组52例和干预组53例。对照组患者实施常规治疗和护理,干预组患者在对照组基础上实施早期护理干预。干预2周后,采用疲劳严重度量表( FSS)判断所有患者是否发生PSF,并检测其血糖、糖化血红蛋白( HbA1c )、 IL-1β、 HDL-C、 LDL-C、 TC及TG。结果干预组患者FSS总分为(2.9±1.5)分,低于对照组的(3.8±1.7)分( P<0.05)。干预组13例患者发生PSF (干预-PSF组),40例患者未发生PSF (干预-非PSF组);对照组23例患者发生PSF (对照-PSF组),29例患者未发生PSF (对照-PSF组)。干预-PSF组血糖、 HbA1c、 IL-1β、 HDL-C高于对照-PSF组和干预-非PSF组,对照-PSF组血糖、 HbA1c、 IL-1β、 HDL-C高于对照-非PSF组( P<0.05)。结论PSF患者血清IL-1β水平明显升高, IL-1β在PSF的发生和发展过程中发挥着重要作用;早期护理干预有助于减少PSF的发生,延缓PSF的发展。
目的:探討腦卒中後疲勞( PSF)患者血清白介素-1β( IL-1β)水平變化及早期護理榦預效果,為PSF的防治提供參攷。方法選取2013年12月—2014年6月我院收治的缺血性腦卒中患者105例,隨機分為對照組52例和榦預組53例。對照組患者實施常規治療和護理,榦預組患者在對照組基礎上實施早期護理榦預。榦預2週後,採用疲勞嚴重度量錶( FSS)判斷所有患者是否髮生PSF,併檢測其血糖、糖化血紅蛋白( HbA1c )、 IL-1β、 HDL-C、 LDL-C、 TC及TG。結果榦預組患者FSS總分為(2.9±1.5)分,低于對照組的(3.8±1.7)分( P<0.05)。榦預組13例患者髮生PSF (榦預-PSF組),40例患者未髮生PSF (榦預-非PSF組);對照組23例患者髮生PSF (對照-PSF組),29例患者未髮生PSF (對照-PSF組)。榦預-PSF組血糖、 HbA1c、 IL-1β、 HDL-C高于對照-PSF組和榦預-非PSF組,對照-PSF組血糖、 HbA1c、 IL-1β、 HDL-C高于對照-非PSF組( P<0.05)。結論PSF患者血清IL-1β水平明顯升高, IL-1β在PSF的髮生和髮展過程中髮揮著重要作用;早期護理榦預有助于減少PSF的髮生,延緩PSF的髮展。
목적:탐토뇌졸중후피로( PSF)환자혈청백개소-1β( IL-1β)수평변화급조기호리간예효과,위PSF적방치제공삼고。방법선취2013년12월—2014년6월아원수치적결혈성뇌졸중환자105례,수궤분위대조조52례화간예조53례。대조조환자실시상규치료화호리,간예조환자재대조조기출상실시조기호리간예。간예2주후,채용피로엄중도량표( FSS)판단소유환자시부발생PSF,병검측기혈당、당화혈홍단백( HbA1c )、 IL-1β、 HDL-C、 LDL-C、 TC급TG。결과간예조환자FSS총분위(2.9±1.5)분,저우대조조적(3.8±1.7)분( P<0.05)。간예조13례환자발생PSF (간예-PSF조),40례환자미발생PSF (간예-비PSF조);대조조23례환자발생PSF (대조-PSF조),29례환자미발생PSF (대조-PSF조)。간예-PSF조혈당、 HbA1c、 IL-1β、 HDL-C고우대조-PSF조화간예-비PSF조,대조-PSF조혈당、 HbA1c、 IL-1β、 HDL-C고우대조-비PSF조( P<0.05)。결론PSF환자혈청IL-1β수평명현승고, IL-1β재PSF적발생화발전과정중발휘착중요작용;조기호리간예유조우감소PSF적발생,연완PSF적발전。
Objective To investigate the changes of serum interleukin -1β( IL-1β) level in patients with post stroke fatigue ( PSF) and effect of early nursing intervention , to provide references for prevention and treatment .Methods From December 2013 to June 2014, 105 patients with ischemic stroke were selected in our hospital , and they were randomly di-vided into control group (n=52) and intervention group (n=53) .Control group given routine treatment and nursing , while intervention group given early nursing intervention based on routine treatment and nursing.After 2 weeks of intervention , fatigue severity scale (FSS) was used to judge PSF, and blood glucose, HbA1c, IL-1β, HDL-C, LDL-C, TC, TG were detec-ted.Results The total score of FSS of intervention group was (2.9 ±1.5), was lower than that of control group of (3.8 ± 1.7) (P<0.05) .In the intervention group, 13 cases occurred PSF (intervention-PSF group), 40 cases did not (interven-tion-non PSF group ); in the control group , 13 cases occurred PSF ( control-PSF group ) , 29 cases did not ( control -non PSF group) .Blood glucose, HbA1c, IL-1β, HDL-C of intervention -PSF group were higher than those of control -PSF group and intervention-non PSF group , and those of control -PSF group were higher than those of control -non PSF group ( P<0.05).Conclusion Serum IL-1βlevel is higher in patients with PSF , which plays a important role in the onset and devel-opment of PSF , and early nursing intervention is helpful to reduce and postpone PSF .