CAJ | 학술논문

目的：观察两性霉素 B 鼻腔内冲洗联合鼻内镜手术治疗真菌性鼻窦炎的效果。方法选择非侵袭性真菌性鼻窦炎患者116例，随机分为鼻内镜手术组（对照组）和两性霉素 B 鼻窦内冲洗联合鼻内镜手术组（试验组）各58例。分别采取单纯鼻内镜手术和两性霉素 B 鼻窦内冲洗联合鼻内镜手术的治疗方法，比较2组患者的治疗效果、治愈时间及术后复发情况。结果试验组治疗效果显著好于对照组；术后愈合时间显著低于对照组；术后12个月复发率显著低于对照组。结论与单纯鼻内镜手术相比，两性霉素 B 鼻窦内冲洗联合鼻内镜手术治疗非侵袭性真菌性鼻窦炎效果较好，提高了治疗有效率，缩短了治愈时间，降低了术后复发率。
목적：관찰량성매소 B 비강내충세연합비내경수술치료진균성비두염적효과。방법선택비침습성진균성비두염환자116례，수궤분위비내경수술조（대조조）화량성매소 B 비두내충세연합비내경수술조（시험조）각58례。분별채취단순비내경수술화량성매소 B 비두내충세연합비내경수술적치료방법，비교2조환자적치료효과、치유시간급술후복발정황。결과시험조치료효과현저호우대조조；술후유합시간현저저우대조조；술후12개월복발솔현저저우대조조。결론여단순비내경수술상비，량성매소 B 비두내충세연합비내경수술치료비침습성진균성비두염효과교호，제고료치료유효솔，축단료치유시간，강저료술후복발솔。
ABSTRACT:Objective To evaluate the effect of nasal endoscopy operation combined with amphotericin B on fungal sinusitis nasal lavage.Methods Non-invasive fungal sinusitis patients 116 cases were randomly divided into endoscopic operation group (control group,n = 58)and amphotericin B sinus lavage combined with endoscopic operation group (experimental group,n =58),the patients were treated either with nasal endoscopic operation or amphotericin B sinus lavage combined with nasal endoscopic operation respectively,the analysis was made on two groups of patients in the treatment efficiency,healing time and postoperative recurrence.Results The effective rate of treatment group was significantly higher than that of control group;the experimental group was significantly lower than the control group after the healing;after 12 months,the recurrence rate of experimental group was significantly lower than that of control group.Conclusion Compared with simple endoscopic sinus operation,amphotericin B washing treatment associated with nasal endoscopic operation on non invasive fungal sinusitis is better in improving the treatment efficiency,as well as reducing the healing time and postoperative recurrence rate.