CAJ | 학술논문

目的：通过对股骨肿瘤患者的回顾性调查，分析其性别、年龄、部位分布特点。方法通过病案查询系统，收集1980年1月—2012年12月资料完整经过手术治疗且有明确病理结果的股骨肿瘤病例，对其性别、年龄、部位分布及类型构成比进行统计学分析，并得出原发性股骨肿瘤性质的独立影响因素。结果共采集股骨肿瘤1504例，其中原发性股骨肿瘤1385例，转移瘤119例，原发性股骨肿瘤高发类型为良性肿瘤，高发部位为股骨远端，高发年龄段为＞10～20岁。良性、恶性高发年龄段均为＞10～20岁，中间型高发年龄段为＞20～30岁。原发股骨恶性肿瘤和转移瘤部位、年龄分布比较差异均有统计学意义（χ2＝226．976，P ＜0．01；χ2＝215．204，P ＜0．01）。有序 Logistic 回归分析显示性别、年龄、部位均是原发性股骨肿瘤性质的独立影响因素（P ＜0．05）。结论原发性股骨肿瘤男性多于女性，多见＞10～20岁，骨肉瘤是最常见的恶性股骨肿瘤，原发性恶性股骨肿瘤主要发生在股骨远端，转移瘤主要发生在股骨近端，性别、年龄、部位均为原发股骨肿瘤性质的独立危险因素，对于45岁以上的女性股骨远端的占位病变临床医生应该引起高度重视。
목적：통과대고골종류환자적회고성조사，분석기성별、년령、부위분포특점。방법통과병안사순계통，수집1980년1월—2012년12월자료완정경과수술치료차유명학병리결과적고골종류병례，대기성별、년령、부위분포급류형구성비진행통계학분석，병득출원발성고골종류성질적독립영향인소。결과공채집고골종류1504례，기중원발성고골종류1385례，전이류119례，원발성고골종류고발류형위량성종류，고발부위위고골원단，고발년령단위＞10～20세。량성、악성고발년령단균위＞10～20세，중간형고발년령단위＞20～30세。원발고골악성종류화전이류부위、년령분포비교차이균유통계학의의（χ2＝226．976，P ＜0．01；χ2＝215．204，P ＜0．01）。유서 Logistic 회귀분석현시성별、년령、부위균시원발성고골종류성질적독립영향인소（P ＜0．05）。결론원발성고골종류남성다우녀성，다견＞10～20세，골육류시최상견적악성고골종류，원발성악성고골종류주요발생재고골원단，전이류주요발생재고골근단，성별、년령、부위균위원발고골종류성질적독립위험인소，대우45세이상적녀성고골원단적점위병변림상의생응해인기고도중시。
ABSTRACT:Objective To analyze the characteristics of femoral tumor cases on sex,age and site through the retrospective study of femoral tumor in our hospital.Methods Through our hospital medical record inquiry system,the femoral tumor cases who had integrity data after operation and had a clear pathological diagnosis of tumor from 1980 January to 2012 December were collected.The sex,age,site and type of constituent ratio were statistically analyzed and the independent risk factors of primary bone malignancy were got.Results One thousand five hundred and four femoral tumor cases were collected,including 1385 cases of primary bone tumors,119 cases of metastatic tumors.Primary bone tumors in high incidence of type of benign tumor,high risk sites were distal femur,the high age of >10- 20 years old.Benign,malignant high risk age was > 10 - 20,intermediate type high risk age ranged > 20 - 30 years old.There were significant differences on the site and age distribution of the primary femoral malignant tumor and metastasis tumor (χ2 = 226.976,P < 0.01;χ2 = 215.204,P < 0.01 ).The logistic regression analysis showed sex,age,and site were independent risk factors of primary bone tumor on malignant degree (P <0.05).Conclusion There were more males than females in the primary bone tumor cases.The highest-risk age group for both sexes was > 10 - 20 years.The most common malignancy of the primary femoral tumor was osteosarcoma.The primary malignant bone tumor mainly occurred in the distal femur and metastases mainly occurred in the proximal femur.The sex,age and site were independent risk factors on malignant degree.Clinicians should pay more attention to females over the age of 45 years old who had space occupying lesions in the distal femur.