国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2014年
12期
1082-1085
,共4页
补气活血汤%椎动脉型颈椎病%疗效评估
補氣活血湯%椎動脈型頸椎病%療效評估
보기활혈탕%추동맥형경추병%료효평고
Buqi-Huoxue decoction%Cervical spondylotic arteriopathy%Therapeutic effect evaluation
目的：评价自拟中药剂“补气活血汤”治疗椎动脉型颈椎病（CSA）的疗效。方法收集2009年3月至2013年11月聊城市复退军人医院诊断明确CSA的门诊患者182例，按就诊顺序（单双号）随机分为治疗组92例、对照组90例。治疗组给予口服自拟补气活血汤；对照组口服盐酸氟桂利嗪胶囊、尼莫地平。两组均治疗30 d。治疗前后应用颈椎病临床评价量表（CASCS）对临床症状、能力和体征进行评分，并经颅多普勒超声（TCD）检查椎动脉（VA）及基底动脉（BA）供血情况，记录收缩期峰值血流速度（Vs）及峰值平均血流速度（Vm），分别观察两组患者的症状变化及动脉供血情况。结果治疗组、对照组患者治疗后CASCS总评分分别为（88.82±5.19）分、（83.46±5.72）分，两组比较差异有统计学意义（P＜0.05）。治疗后60岁以下者TCD：治疗组左侧椎动脉（LVA）、右侧椎动脉（RVA）、基底动脉（BA）Vs值分别为（50.52±6.86）cm/s、（49.14±5.81）cm/s、（57.20±5.37）cm/s 均低于对照组[（53.70±8.14）cm/s、（51.67±7.45）cm/s、（59.76±5.11）cm/s]，两组比较差异有统计学意义（P＜0.05）。≥60岁者，治疗组LVA、RVA、BA的Vs值分别为（40.37±2.24）cm/s、（40.78±1.85）cm/s、（51.04±3.81）cm/s均高于对照组[分别为（37.58±2.86）cm/s、（37.58±2.72）cm/s、（46.92±5.26）cm/s]，两组比较差异有统计学意义（P＜0.05）。治疗组总有效率为97.83%（90/92）、对照组为88.89%（80/98），两组比较差异有统计学意义（χ2＝13.743， P＝0.01）。结论自拟补气活血汤治疗椎动脉型颈椎病有效。
目的：評價自擬中藥劑“補氣活血湯”治療椎動脈型頸椎病（CSA）的療效。方法收集2009年3月至2013年11月聊城市複退軍人醫院診斷明確CSA的門診患者182例，按就診順序（單雙號）隨機分為治療組92例、對照組90例。治療組給予口服自擬補氣活血湯；對照組口服鹽痠氟桂利嗪膠囊、尼莫地平。兩組均治療30 d。治療前後應用頸椎病臨床評價量錶（CASCS）對臨床癥狀、能力和體徵進行評分，併經顱多普勒超聲（TCD）檢查椎動脈（VA）及基底動脈（BA）供血情況，記錄收縮期峰值血流速度（Vs）及峰值平均血流速度（Vm），分彆觀察兩組患者的癥狀變化及動脈供血情況。結果治療組、對照組患者治療後CASCS總評分分彆為（88.82±5.19）分、（83.46±5.72）分，兩組比較差異有統計學意義（P＜0.05）。治療後60歲以下者TCD：治療組左側椎動脈（LVA）、右側椎動脈（RVA）、基底動脈（BA）Vs值分彆為（50.52±6.86）cm/s、（49.14±5.81）cm/s、（57.20±5.37）cm/s 均低于對照組[（53.70±8.14）cm/s、（51.67±7.45）cm/s、（59.76±5.11）cm/s]，兩組比較差異有統計學意義（P＜0.05）。≥60歲者，治療組LVA、RVA、BA的Vs值分彆為（40.37±2.24）cm/s、（40.78±1.85）cm/s、（51.04±3.81）cm/s均高于對照組[分彆為（37.58±2.86）cm/s、（37.58±2.72）cm/s、（46.92±5.26）cm/s]，兩組比較差異有統計學意義（P＜0.05）。治療組總有效率為97.83%（90/92）、對照組為88.89%（80/98），兩組比較差異有統計學意義（χ2＝13.743， P＝0.01）。結論自擬補氣活血湯治療椎動脈型頸椎病有效。
목적：평개자의중약제“보기활혈탕”치료추동맥형경추병（CSA）적료효。방법수집2009년3월지2013년11월료성시복퇴군인의원진단명학CSA적문진환자182례，안취진순서（단쌍호）수궤분위치료조92례、대조조90례。치료조급여구복자의보기활혈탕；대조조구복염산불계리진효낭、니막지평。량조균치료30 d。치료전후응용경추병림상평개량표（CASCS）대림상증상、능력화체정진행평분，병경로다보륵초성（TCD）검사추동맥（VA）급기저동맥（BA）공혈정황，기록수축기봉치혈류속도（Vs）급봉치평균혈류속도（Vm），분별관찰량조환자적증상변화급동맥공혈정황。결과치료조、대조조환자치료후CASCS총평분분별위（88.82±5.19）분、（83.46±5.72）분，량조비교차이유통계학의의（P＜0.05）。치료후60세이하자TCD：치료조좌측추동맥（LVA）、우측추동맥（RVA）、기저동맥（BA）Vs치분별위（50.52±6.86）cm/s、（49.14±5.81）cm/s、（57.20±5.37）cm/s 균저우대조조[（53.70±8.14）cm/s、（51.67±7.45）cm/s、（59.76±5.11）cm/s]，량조비교차이유통계학의의（P＜0.05）。≥60세자，치료조LVA、RVA、BA적Vs치분별위（40.37±2.24）cm/s、（40.78±1.85）cm/s、（51.04±3.81）cm/s균고우대조조[분별위（37.58±2.86）cm/s、（37.58±2.72）cm/s、（46.92±5.26）cm/s]，량조비교차이유통계학의의（P＜0.05）。치료조총유효솔위97.83%（90/92）、대조조위88.89%（80/98），량조비교차이유통계학의의（χ2＝13.743， P＝0.01）。결론자의보기활혈탕치료추동맥형경추병유효。
Objective To evaluate the therapeutic effect of Buqi-Huoxue decoction on cervical spondylotic arteriopathy(CSA). Methods 182 patients were diagnosed with CSA in our hospital during the period of March 2009 to November 2013. Among which 92 cases were assigned to a test group(outpatients) and 90 cases to a control group. The test group was treated with traditional Chinese medicine Buqi-Huoxue decoction, while the control group was treated with flunarizine and nimodipine. The level of seriousness of the symptoms, abilities and physical signs were recorded by clinical assessment scale for cervical spondylosis(CASCS), and velocity of blood flow at systolic peak(Vs)and mean blood flow velocity(Vm) of vertebral arteries(VA)and basilar artery(BA)were measured by transcranial doppler(TCD) monitoring to evaluate the blood supply before and after the treatment. After 30 days of treatment, CASCS and the TCD were recorded again to observe the clinical symptoms and the degree of blood supply improvement, and then the data were analyzed to value the curative effect. Results CASCS score of the two groups was 88.82±5.19, and 83.46±5.72 respectively, with P<0.05. The TCD results showed that, the patients less than 60 years old in the test group had Vs values of LVA, RVA and BA at(50.52±6.86)cm/s,(49.14±5.81)cm/s,(57.20± 5.37)cm/s after the treatment, and these values of the control group were(53.70±8.14)cm/s, (51.67±7.45)cm/s, (59.76±5.11)cm/s respectively;while patients over 60 years old in the test group had Vs values of LVA, RVA and BA at(40.37±2.24)cm/s, (40.78±1.85)cm/s, (51.04±3.81)cm/s after the treatment, these values of the control group were(37.58±2.86)cm/s, (37.58±2.72)cm/s, (46.92±5.26)cm/s respectively. The effective rate of the test group was 97.83%, while the value was 88.89%of the control group, which also showed a significant difference(χ2=13.743, P=0.01). Conclusion More significant effects of Buqi-Huoxue decoction for treating disease of CSA was achieved compared with the treatment of flunarizine and nimodipine.
