CAJ | 학술논문

目的：观察达立通联合三联杀菌疗法根除慢性胃炎幽门螺杆菌(Hp)感染的临床疗效。方法：将120例患者随机分为2组：治疗组60例予达立通联合三联疗法治疗，对照组60例予三联疗法治疗，观察2组治疗前后临床症状及Hp根除情况。结果：Hp根除率治疗组为84.48%，对照组为68.42%，2组比较差异有统计学意义(P＜0.05)。治疗组各个症状积分治疗前后比较，差异有统计学意义(P＜0.05)。对照组胃脘疼痛、烧心反酸的症状积分治疗前后比较，差异有统计学意义(P＜0.05)；胃胀痞满、纳呆食少、嗳气的症状积分治疗前后比较，差异无统计学意义(P＞0.05)。2组治疗后烧心反酸症状积分比较，差异无统计学意义(P＞0.05)；其他症状积分比较，差异有统计学意义(P＜0.05)。结论：达立通联合三联疗法根除慢性胃炎患者Hp感染疗效明显，能有效改善临床症状。
목적：관찰체립통연합삼련살균요법근제만성위염유문라간균(Hp)감염적림상료효。방법：장120례환자수궤분위2조：치료조60례여체립통연합삼련요법치료，대조조60례여삼련요법치료，관찰2조치료전후림상증상급Hp근제정황。결과：Hp근제솔치료조위84.48%，대조조위68.42%，2조비교차이유통계학의의(P＜0.05)。치료조각개증상적분치료전후비교，차이유통계학의의(P＜0.05)。대조조위완동통、소심반산적증상적분치료전후비교，차이유통계학의의(P＜0.05)；위창비만、납태식소、애기적증상적분치료전후비교，차이무통계학의의(P＞0.05)。2조치료후소심반산증상적분비교，차이무통계학의의(P＞0.05)；기타증상적분비교，차이유통계학의의(P＜0.05)。결론：체립통연합삼련요법근제만성위염환자Hp감염료효명현，능유효개선림상증상。
Objective:To observe curative effects of DaLiTong granules and triple therapy in eradicating Heli-cobacter pylori (Hp) infection of the patients with chronic gastritis (CG). Methods:Altogether 120 patients were ran-domly divided into two group:the treatment group were administered with DaLiTong granules and triple therapy, the control group triple therapy, clinical symptoms and Hp eradication of both groups were observed before and after treating. Results:Hp eradication rate of the treatment group was 84.48%, higher than 68.42%of the control group, the difference had statistical meaning (P<0.05). It also showed statistical meaning in symptom scales between be-fore and after treating in the treatment group (P<0.05). It demonstrated statistical meaning in symptom scales such as stomachache, heartburn and sour regurgitation between before and after treating in the control group (P<0.05). The difference had no statistical meaning in the comparison of symptom scales including gastric distension and full-ness, anorexia and poor appetite, belching between before and after treating (P>0.05). The difference had no no sta-tistical meaning in the comparison of syptom scales such as heartburn and sour regurgitation between both groups af-ter treating (P>0.05);the difference demonstrated statistical meaning in the comparison of other symptom scales (P<0.05). Conclusion:DaLiTong granules and triple therapy are effective in eradicating Hp infection of CG patients, and the therapy could effectively improve clinical symptoms of the patients.