CAJ | 학술논문

目的：观察怡肾抗凝散穴位贴敷治疗肾病综合征的临床疗效。方法：将112例患者随机分为治疗组60例、对照组52例。对照组给予低盐、低脂、优质、低蛋白饮食，联合激素口服及环磷酰胺(CTX)治疗，治疗组在对照组治疗的基础上给予怡肾抗凝散穴位贴敷双侧肾俞、膀胱俞及膏肓俞。2组总疗程均为半年，治疗期间均未采用其他针对本病的治疗措施。观察2组治疗前、治疗后2个月、治疗后3个月及治疗后半年时血小板计数(Plt)、纤维蛋白原定量(Fib)、白蛋白(Alb)、总胆固醇(TC)及甘油三酯(TG)的变化情况。结果：总有效率治疗组为96.67%，对照组为88.46%，2组比较差异显著(P＜0.05)。 Alb、TC、TG、Plt及Fib治疗前后组内比较，2组均有统计学意义(P＜0.05)；治疗后2个月，治疗组与对照组相比，Alb、TC、TG、Plt及Fib均无统计学意义(P＞0.05)；治疗后3个月比较，TC、TG无统计学意义(P＞0.05)，Alb、Plt、Fib有统计学意义(P＜0.05)；治疗后6个月比较，Alb、TC、TG、Plt及Fib均有统计学意义(P＜0.05)。结论：怡肾抗凝散穴位贴敷能够改善患者的高凝倾向。
목적：관찰이신항응산혈위첩부치료신병종합정적림상료효。방법：장112례환자수궤분위치료조60례、대조조52례。대조조급여저염、저지、우질、저단백음식，연합격소구복급배린선알(CTX)치료，치료조재대조조치료적기출상급여이신항응산혈위첩부쌍측신유、방광유급고황유。2조총료정균위반년，치료기간균미채용기타침대본병적치료조시。관찰2조치료전、치료후2개월、치료후3개월급치료후반년시혈소판계수(Plt)、섬유단백원정량(Fib)、백단백(Alb)、총담고순(TC)급감유삼지(TG)적변화정황。결과：총유효솔치료조위96.67%，대조조위88.46%，2조비교차이현저(P＜0.05)。 Alb、TC、TG、Plt급Fib치료전후조내비교，2조균유통계학의의(P＜0.05)；치료후2개월，치료조여대조조상비，Alb、TC、TG、Plt급Fib균무통계학의의(P＞0.05)；치료후3개월비교，TC、TG무통계학의의(P＞0.05)，Alb、Plt、Fib유통계학의의(P＜0.05)；치료후6개월비교，Alb、TC、TG、Plt급Fib균유통계학의의(P＜0.05)。결론：이신항응산혈위첩부능구개선환자적고응경향。
Objective:To observe curative effects of YiShen KangNing powder strapping in the treatment for nephrotic syndrome. Methods:All 112 patients were randomly divided into 60 cases of the treatment group and 52 cases of the control group. The control group were given with low salt, low fat, high quality, low protein diet, oral administration of hormone and CTX, the treatment group received acupoint application of YiShen KangNing powder to ShenShu (BL23), PangGuangShu (BL28) and GaoMangShu (BL43) bilaterally. The whole courses of the treatment for both groups were half of one year, other therapeutic measures were not given to the patients during therapeutic courses. The changes of platelet count (Plt), quantitative fibrinogen (Fib), albumin (Alb), total cholesterol (TC) and triglyceride (TG) in both groups were observed before treating, in two months, three months and half of the year after treating. Results:Total effective rate of the treatment group was 96.67%, higher than 88.46%of the control group with significant difference (P<0.05). The comparison in Alb, TC, TG, Plt and Fib between before and after treating had statistical meaning in both groups (P<0.05);in two months after treating, the comparison between both groups had no statistical meaning in Alb, TC, TG, Plt and Fib (P>0.05);the comparison had no statistical meaning in TC and TG in three months after treating (P>0.05), it showed statistical meaning in Alb, Plt and Fib (P<0.05);the comparison had statistical meaning in Alb, TC, TG, Plt and Fib in six months after treating (P<0.05). Conclusion:YiShen KangNing powder strapping could improve hypercoagulation inclination of the patients.