中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2014年
36期
31-32
,共2页
糖化白蛋白%2型糖尿病%颈动脉斑块
糖化白蛋白%2型糖尿病%頸動脈斑塊
당화백단백%2형당뇨병%경동맥반괴
Glycated albumin%Type 2 diabetes mellitus%Carotid plaque
目的：探讨2型糖尿病(T2DM)患者血清糖化白蛋白(GA)水平与颈动脉斑块之间的相关性。方法156例住院的T2DM患者,所有患者均行颈动脉超声检查,测量颈动脉内中膜厚度(IMT),并检测GA及相关生化指标,根据有无颈动脉斑块分为A组(无颈动脉斑块者,84例)和B组(有颈动脉斑块者,72例),并进行相关统计学分析。结果 B组的GA水平显著高于A组, GA与IMT之间呈显著正相关(P<0.05)。Logistic多元回归分析表明, GA及糖化血红蛋白是颈动脉斑块的独立危险因素(P<0.05)。结论 GA与T2DM患者的颈动脉斑块之间关系密切,可以作为预测T2DM大血管病变的临床指标。
目的：探討2型糖尿病(T2DM)患者血清糖化白蛋白(GA)水平與頸動脈斑塊之間的相關性。方法156例住院的T2DM患者,所有患者均行頸動脈超聲檢查,測量頸動脈內中膜厚度(IMT),併檢測GA及相關生化指標,根據有無頸動脈斑塊分為A組(無頸動脈斑塊者,84例)和B組(有頸動脈斑塊者,72例),併進行相關統計學分析。結果 B組的GA水平顯著高于A組, GA與IMT之間呈顯著正相關(P<0.05)。Logistic多元迴歸分析錶明, GA及糖化血紅蛋白是頸動脈斑塊的獨立危險因素(P<0.05)。結論 GA與T2DM患者的頸動脈斑塊之間關繫密切,可以作為預測T2DM大血管病變的臨床指標。
목적：탐토2형당뇨병(T2DM)환자혈청당화백단백(GA)수평여경동맥반괴지간적상관성。방법156례주원적T2DM환자,소유환자균행경동맥초성검사,측량경동맥내중막후도(IMT),병검측GA급상관생화지표,근거유무경동맥반괴분위A조(무경동맥반괴자,84례)화B조(유경동맥반괴자,72례),병진행상관통계학분석。결과 B조적GA수평현저고우A조, GA여IMT지간정현저정상관(P<0.05)。Logistic다원회귀분석표명, GA급당화혈홍단백시경동맥반괴적독립위험인소(P<0.05)。결론 GA여T2DM환자적경동맥반괴지간관계밀절,가이작위예측T2DM대혈관병변적림상지표。
Objective To investigate the correlation between glycated albumin (GA) level and carotid plaque in type 2 diabetes mellitus (T2DM) patients. Methods A total of 156 T2DM patients received carotid ultrasound examination. Intima media thickness was measured, and GA and related biochemical criterion were detected. According to the occurrence of carotid plaque, patients were divided into group A (84 cases without carotid plaque) and group B (72 cases with carotid plaque). Related statistical analysis was performed. Results The group B had higher GA level than the group A, and GA was positively correlated with IMT (P<0.05). The results of Logistic regression analysis showed that GA and glycosylated hemoglobin were the independent risk factors of carotid plaque (P<0.05). Conclusion There is a close relation between GA and carotid plaque in T2DM patients, and GA can be used as the clinical index for predicting macroangiopathy in T2DM.
