中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2014年
35期
5-6
,共2页
非酒精性脂肪肝%危险因素%体质量指数%代谢综合征
非酒精性脂肪肝%危險因素%體質量指數%代謝綜閤徵
비주정성지방간%위험인소%체질량지수%대사종합정
Non-alcoholic fatty liver disease%Risk factors%Body mass index%Metabolic syndrome
目的：分析非酒精性脂肪肝(NAFLD)患者临床指标,探讨其相关危险因素。方法180例体检患者按有无NAFLD分为正常对照组(86例)和NAFLD组(94例),对两组各临床指标进行统计分析。结果与对照组比较, NAFLD组体质量指数(BMI)、腰围、丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)、γ-谷氨酰转肽酶(GGT)、血脂总胆固醇(TC)、甘油三酯(TG)、非高密度脂蛋白胆固醇(non-HDL-C)、空腹血糖(FBG)、尿酸、收缩压(SBP)、舒张压(DBP)均显著升高,而高密度脂蛋白胆固醇(HDL-C)显著降低(P<0.05)。Logistic回归分析显示BMI、腰围、TG可较好地预测NAFLD,是NAFLD的独立危险因素(P<0.05)。结论 NAFLD患者具有中心性肥胖、高血糖、高血压、脂代谢紊乱(高TC、高TG、低HDL-C)、高尿酸的特征,且肝酶升高。BMI、腰围、TG是发生NAFLD的独立危险因素。
目的：分析非酒精性脂肪肝(NAFLD)患者臨床指標,探討其相關危險因素。方法180例體檢患者按有無NAFLD分為正常對照組(86例)和NAFLD組(94例),對兩組各臨床指標進行統計分析。結果與對照組比較, NAFLD組體質量指數(BMI)、腰圍、丙氨痠轉氨酶(ALT)、天鼕氨痠轉氨酶(AST)、γ-穀氨酰轉肽酶(GGT)、血脂總膽固醇(TC)、甘油三酯(TG)、非高密度脂蛋白膽固醇(non-HDL-C)、空腹血糖(FBG)、尿痠、收縮壓(SBP)、舒張壓(DBP)均顯著升高,而高密度脂蛋白膽固醇(HDL-C)顯著降低(P<0.05)。Logistic迴歸分析顯示BMI、腰圍、TG可較好地預測NAFLD,是NAFLD的獨立危險因素(P<0.05)。結論 NAFLD患者具有中心性肥胖、高血糖、高血壓、脂代謝紊亂(高TC、高TG、低HDL-C)、高尿痠的特徵,且肝酶升高。BMI、腰圍、TG是髮生NAFLD的獨立危險因素。
목적：분석비주정성지방간(NAFLD)환자림상지표,탐토기상관위험인소。방법180례체검환자안유무NAFLD분위정상대조조(86례)화NAFLD조(94례),대량조각림상지표진행통계분석。결과여대조조비교, NAFLD조체질량지수(BMI)、요위、병안산전안매(ALT)、천동안산전안매(AST)、γ-곡안선전태매(GGT)、혈지총담고순(TC)、감유삼지(TG)、비고밀도지단백담고순(non-HDL-C)、공복혈당(FBG)、뇨산、수축압(SBP)、서장압(DBP)균현저승고,이고밀도지단백담고순(HDL-C)현저강저(P<0.05)。Logistic회귀분석현시BMI、요위、TG가교호지예측NAFLD,시NAFLD적독립위험인소(P<0.05)。결론 NAFLD환자구유중심성비반、고혈당、고혈압、지대사문란(고TC、고TG、저HDL-C)、고뇨산적특정,차간매승고。BMI、요위、TG시발생NAFLD적독립위험인소。
Objective To analyze the clinical index of patients with non-alcoholic fatty liver disease (NAFLD), and to explore its related risk factors.Methods A total of 180 physical examination patients were divided into normal control group (86 cases) and NAFLD group (94 cases), according to their condition of having NAFLA or not. The clinical indexes were statistically analyzed in the two groups.Results Compared with the control group, the levels of body mass index (BMI), waistline, alanine aminotransferase (ALT), aspartate transaminase (AST), γ-gamma glutamyl transpeptidase (GGT), total cholesterol (TC), triglyceride (TG), non high density lipoprotein cholesterol (non-HDL-C), fasting blood glucose (FBG), uric acid, systolic blood pressure (SBP), and diastolic blood pressure (DBP) were significantly increased in the NAFLD group, and the level of high-density lipoprotein cholesterol (HDL-C) was decreased obviously (P<0.05). Logistic regression analysis indicated that BMI, waistline, and TG level could effectively predict NAFLD, and they were the independent risk factors of NAFLD (P<0.05).Conclusion NAFLD patients have the features of central obesity, hyperglycemia, hypertension, dyslipidemia (high levels of TC and TG, low level of HDL-C), hypeluricemia, and elevated liver enzymes. The independent risk factors of NAFLD are BMI, waistline and TG.
