中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
35期
34-35
,共2页
门冬氨酸钾镁%蒽环类药物%化疗%心脏毒性
門鼕氨痠鉀鎂%蒽環類藥物%化療%心髒毒性
문동안산갑미%은배류약물%화료%심장독성
Potassium magnesium aspartate%Anthracycline drugs%Chemotherapy%Cardiac toxicity
目的：探讨患者预防性使用门冬氨酸钾镁改善蒽环类化疗药物对心脏的毒性评价。方法：本组肿瘤患者82例，治疗组42例在应用蒽环类药物同时使用门冬氨酸钾镁20 mL+5%葡萄糖溶液500 mL静滴，对照组40例单用化疗药物。比较两组心电图改变及LVEF改变。结果：两组在心电图改变差异有统计学意义(P＜0.05)，两组LVEF改变差异有统计学意义(P＜0.05)。结论：预防性使用门冬氨酸钾镁对蒽环类药物的心脏毒性有一定的保护作用。
目的：探討患者預防性使用門鼕氨痠鉀鎂改善蒽環類化療藥物對心髒的毒性評價。方法：本組腫瘤患者82例，治療組42例在應用蒽環類藥物同時使用門鼕氨痠鉀鎂20 mL+5%葡萄糖溶液500 mL靜滴，對照組40例單用化療藥物。比較兩組心電圖改變及LVEF改變。結果：兩組在心電圖改變差異有統計學意義(P＜0.05)，兩組LVEF改變差異有統計學意義(P＜0.05)。結論：預防性使用門鼕氨痠鉀鎂對蒽環類藥物的心髒毒性有一定的保護作用。
목적：탐토환자예방성사용문동안산갑미개선은배류화료약물대심장적독성평개。방법：본조종류환자82례，치료조42례재응용은배류약물동시사용문동안산갑미20 mL+5%포도당용액500 mL정적，대조조40례단용화료약물。비교량조심전도개변급LVEF개변。결과：량조재심전도개변차이유통계학의의(P＜0.05)，량조LVEF개변차이유통계학의의(P＜0.05)。결론：예방성사용문동안산갑미대은배류약물적심장독성유일정적보호작용。
Objective:To investigate the evaluation of prophylactic use of Potassium Aspartate magnesium improving anthracycline cardiac toxicity of patients.Methods:82 patients with tumor were selected.The treatment group with 42 cases were treated with anthracene ring drugs at the same time used potassium aspartate magnesium 20 mL+5%GS 500 mL intravenous drip, and the control group with 40 cases were only with chemotherapy drugs.Results:The two groups had very significant differences in the ECG change(P<0.05);the LVEF change of two groups had significant difference(P<0.05).Conclusion:The prophylactic use of Potassium Aspartate magnesium drugs on the cardiac toxicity of anthracene ring has protective effect.
