CAJ | 학술논문

目的：探讨阻塞性睡眠暂停低通气综合征（ OSAHS）患者血液中的肾素、血管紧张素水平异常和高血压之间关系。方法：选取住院接收治疗的100例患者，将患者随机分成两组，观察组患者伴有高血压，共50例，对比组非OSAHS患者，共有50例。对两组患者均采取晨起觉醒时抽静脉血2m1，用放射免疫法检测肾素、血管紧张素，分析采集数据，通过样本结果的分析、比较两组患者检测结果的差异性。结果：经过检验发现观察组患者血浆肾素、血管紧张素水平明显高于对照组（ P﹤0.05）。结论：OSAHS伴有高血压患者，肾素、血管紧张素-醛固酮系统（ RAAS）过度激活，睡眠觉醒、OSA可导致患者交感神经的兴奋，导致RAAS系统的激活，释放的儿茶酚胺、肾素、血管紧张素Ⅱ、醛固酮可导致患者血压的上升。
목적：탐토조새성수면잠정저통기종합정（ OSAHS）환자혈액중적신소、혈관긴장소수평이상화고혈압지간관계。방법：선취주원접수치료적100례환자，장환자수궤분성량조，관찰조환자반유고혈압，공50례，대비조비OSAHS환자，공유50례。대량조환자균채취신기각성시추정맥혈2m1，용방사면역법검측신소、혈관긴장소，분석채집수거，통과양본결과적분석、비교량조환자검측결과적차이성。결과：경과검험발현관찰조환자혈장신소、혈관긴장소수평명현고우대조조（ P﹤0.05）。결론：OSAHS반유고혈압환자，신소、혈관긴장소-철고동계통（ RAAS）과도격활，수면각성、OSA가도치환자교감신경적흥강，도치RAAS계통적격활，석방적인다분알、신소、혈관긴장소Ⅱ、철고동가도치환자혈압적상승。
Objective This paper main1Y discusses the suffering from obstructive s1eep apnea hYpopnea sYndrome( OSAHS)patients with hYpertension re1ationship between. renin,angiotensin 1eve1s. Methods 100 patients were se1ected,the patients were random1Y divided into two groups,the observation group patients with hYpertension,50 cases,comparison group of patients with OSAHS a1one,a tota1 of 50 ca_ses. On two groups of patients who tooK were taKen venous b1ood 2m1 ear1Y morning awaKening,radioimmunoassaY was used to measure the renin,angiotensin,ana1Ysis of the data co11ected,the test resu1t difference between the two groups were compared bY ana1Ysis of sam_p1es. Results Through the inspection found that the observation group patients p1asma renin,angiotensin 1eve1s were significant1Y higher than those in the comparison group( P﹤0. 05). conclusion For the OSAHS associated with hYpertension,renin,angiotensin - a1dosterone sYstem( RAAS)was activated;repeated OSA,s1eep awaKening increased sYmpathetic activitY,therebY promoting the activation of renin re_1ease RAAS,catecho1amine,renin,angiotensin,a1dosterone secretion increases the incidence of hYpertensio.