CAJ | 학술논문

人类体质及运动能力与其他性状一样，属于多基因调控。从决定人体有氧运动能力的生理学基础上看，血液中红细胞、血红蛋白的携氧、运氧能力起着非常重要的作用。而人体中红细胞的产生是受基因调控的，主要受促红细胞生成素(EPO)基因和促红细胞生成素受体（EPOR）基因作用。只有促红细胞生成素（EPO）和促红细胞生成素受体（EPOR）结合，引发一系列信号传导，最终启动相关基因转录，生成网织红细胞和红细胞。因此，研究促红细胞生成素受体（EPOR）基因的多态性与红细胞、血红蛋白的关系，对于评定运动员的有氧能力及作为选取耐力项目运动员的指标是非常有意义的。
인류체질급운동능력여기타성상일양，속우다기인조공。종결정인체유양운동능력적생이학기출상간，혈액중홍세포、혈홍단백적휴양、운양능력기착비상중요적작용。이인체중홍세포적산생시수기인조공적，주요수촉홍세포생성소(EPO)기인화촉홍세포생성소수체（EPOR）기인작용。지유촉홍세포생성소（EPO）화촉홍세포생성소수체（EPOR）결합，인발일계렬신호전도，최종계동상관기인전록，생성망직홍세포화홍세포。인차，연구촉홍세포생성소수체（EPOR）기인적다태성여홍세포、혈홍단백적관계，대우평정운동원적유양능력급작위선취내력항목운동원적지표시비상유의의적。
Physique and kinetism of human is similar with other traits,belongs to multi gene regulation. From the physiological basis which decided physiological aerobic kinetism of human,carrying and transporting oxygen ability of red blood cell and hemoglobin in the blood plays a very important role. However,red blood cell in the human body is regulated by gene,mainly by erythropoietin (EPO) gene and erythropoietin receptor (EPOR) gene. Only the erythropoietin (EPO) and erythropoietin receptor (EPOR) combing,priming a series of signal transduction,finally promoting related gene transcription, create reticulocytes and erythrocytes. Therefore,studying on the relationship of erythropoietin receptor (EPOR) gene polymorphism and red blood cell,hemoglobin,which is very meaningful for evaluation of aerobic capacity of athletes and as a selection index for athletes.