CAJ | 학술논문

Nogo-A在神经系统损伤后可抑制轴突再生，导致神经系统的不可逆性损伤，这一机制已被广泛认可。但是No-go-A对神经系统的作用仍有争议。神经元是神经系统的重要组成部分，占据神经系统约10%左右，由胞体和神经突组成，神经突又可以分为树突和轴突，神经元主要功能是接受刺激和传递信息。近几年的研究发现， Nogo-A对神经元起着保护和促进成熟的作用，本文综述Nogo-A对神经元的主要作用。
Nogo-A재신경계통손상후가억제축돌재생，도치신경계통적불가역성손상，저일궤제이피엄범인가。단시No-go-A대신경계통적작용잉유쟁의。신경원시신경계통적중요조성부분，점거신경계통약10%좌우，유포체화신경돌조성，신경돌우가이분위수돌화축돌，신경원주요공능시접수자격화전체신식。근궤년적연구발현， Nogo-A대신경원기착보호화촉진성숙적작용，본문종술Nogo-A대신경원적주요작용。
Nogo-A can inhibit the axon regeneration after nervous system injury, which causes irreversible damage of the nervous system. This mechanism is widely recognized. But the influence of Nogo-A on the function of nervous system is still controversial. Neuron is an important part of the nervous system, occupying about 10% of the nervous system, which is composed of cell body and neurite, and neurite can be divided into dendrite and axon. The main function of neuron is to accept stimuli and to convey information. In recent years, the study indicated that Nogo-A can protect and promote neuron to mature and this article was to give a review on the influence of Nogo-A on neuron.