CAJ | 학술논문

目的：评估综合干预方法对接受免费服药的精神分裂症患者疗效的影响。方法选取500例贫困精神分裂症患者，随机分为2个组，每组各250名病人，干预组的病人每月由专业医生随访发药并实施综合干预措施，对照组的病人每月在社区集中取药。随访3年，分析两组病人临床疗效、社会功能、幸福感指数、监护率、复发率、再住院次数及肇事肇祸情况。结果干预组病人在疾病疗效、社会功能、幸福感指数上显著优于对照组组（P<0.05）；在年均复发次数、年均住院次数、肇事肇祸次数上均呈下降趋势，具有统计学意义。结论综合干预方法能提高免费服药的精神分裂症患者的疗效和幸福感，能减少复发，改善患者的社会功能。
목적：평고종합간예방법대접수면비복약적정신분렬증환자료효적영향。방법선취500례빈곤정신분렬증환자，수궤분위2개조，매조각250명병인，간예조적병인매월유전업의생수방발약병실시종합간예조시，대조조적병인매월재사구집중취약。수방3년，분석량조병인림상료효、사회공능、행복감지수、감호솔、복발솔、재주원차수급조사조화정황。결과간예조병인재질병료효、사회공능、행복감지수상현저우우대조조조（P<0.05）；재년균복발차수、년균주원차수、조사조화차수상균정하강추세，구유통계학의의。결론종합간예방법능제고면비복약적정신분렬증환자적료효화행복감，능감소복발，개선환자적사회공능。
Objective: To evaluate the efficacy of free distributing drug in synthetic intervention way to the schizophrenics. Methods: Selected 500 poor schizophrenics by district and randomly divided them into two groups, each team has 250 patients. The patients in intervention group got drug from professional doctors and treated by them monthly. The patients in non-intervention group got drug from Community Health Center quarterly. After distributed free drug for 3 years, all patients in two groups were evaluated with the CGI evaluation, Social Disability Screening Schedule (SDSS), General Well-Being Schedule (GWB) and then they were assessed Guardianship rate, relapse rate, re-hospitalization rate and trouble- making rate. Result: Compared with patients in non-intervention group, the treating effectiveness, social function and General Well-Being Index were significantly superior in intervention group at the end of study (P<0.05). In the relapse rate, re-hospitalization rate and troublemaking times appears a declined trend in intervention group during 3 years.Conclusion: Free distributing drug in synthetic intervention way can reduce relapse rate and improve the schizophrenics’ compliance, feeling of happiness and social function.