药学研究
藥學研究
약학연구
JOURNAL OF PHARMACEUTICAL RESEARCH
2014年
12期
702-704
,共3页
质量标准%头痛宁颗粒%薄层色谱法%高效液相色谱法%天麻素
質量標準%頭痛寧顆粒%薄層色譜法%高效液相色譜法%天痳素
질량표준%두통저과립%박층색보법%고효액상색보법%천마소
Quality standard%Toutongning Granules%TLC%HPLC%Gastrodin
目的:建立头痛宁颗粒质量标准。方法采用薄层色谱法对制剂中的天麻、当归、防风进行薄层鉴别;采用高效液相色谱法对制剂中的天麻素进行含量测定。结果在薄层色谱图中可检出天麻、当归、防风;天麻素在0.1136~2.272μg范围内与峰面积呈良好的线性关系( r=0.9996),平均回收率为98.9%,RSD为1.48%。结论所建立的方法可靠、准确、专属性强,可有效控制头痛宁颗粒的质量。
目的:建立頭痛寧顆粒質量標準。方法採用薄層色譜法對製劑中的天痳、噹歸、防風進行薄層鑒彆;採用高效液相色譜法對製劑中的天痳素進行含量測定。結果在薄層色譜圖中可檢齣天痳、噹歸、防風;天痳素在0.1136~2.272μg範圍內與峰麵積呈良好的線性關繫( r=0.9996),平均迴收率為98.9%,RSD為1.48%。結論所建立的方法可靠、準確、專屬性彊,可有效控製頭痛寧顆粒的質量。
목적:건립두통저과립질량표준。방법채용박층색보법대제제중적천마、당귀、방풍진행박층감별;채용고효액상색보법대제제중적천마소진행함량측정。결과재박층색보도중가검출천마、당귀、방풍;천마소재0.1136~2.272μg범위내여봉면적정량호적선성관계( r=0.9996),평균회수솔위98.9%,RSD위1.48%。결론소건립적방법가고、준학、전속성강,가유효공제두통저과립적질량。
Objective To establish the quality standard for Toutongning Granules. Methods The Gastrodia elata,An-gelica sinensis( Oliv)Diels,Saposhnikovia divaricata( Turcz)Schischk. were identified by TLC;The content of Gastrodin was dentermined by HPLC. Results The Gastrodia elata,Angelica sinensis( Oliv),Saposhnikovia divaricata( Turcz)were detected by TLC . The linear range of Gastrodin was 0. 113 6 ~2. 272 μg( r =0. 999 6 ),and the average recovery was 98. 9% with RSD 1. 48%. Conclusions The method was reliable,specifie and accurate,and can effectively control the quality of Toutongning Granules.