中西医结合心脑血管病杂志
中西醫結閤心腦血管病雜誌
중서의결합심뇌혈관병잡지
CHINESE JOURNAL OF INTEGRATIVE MEDICINE ON CARDIO-/CEREBROVASCULAR DISEASE
2014年
12期
1450-1452
,共3页
广泛性焦虑症%加味温胆肠%痰热内扰
廣汎性焦慮癥%加味溫膽腸%痰熱內擾
엄범성초필증%가미온담장%담열내우
generalized anxiety disorder%Jiawei Wendan decoction%phlegm heat syndrome
目的：观察加味温胆汤治疗痰热内扰型广泛性焦虑症的临床疗效及不良反应。方法将90例符合纳入标准的痰热内扰型广泛性焦虑症患者随机分为中药组、西药组、中西药组进行观察,中药组给予加味温胆汤每日1剂,早晚分两次口服；西药组给予帕罗西汀20 mg,每日1次口服；中西药组给予加味温胆汤,每日1剂,帕罗西汀20 mg,每日1次口服。观察4周后评定疗效。结果中西药联合治疗在汉密尔顿焦虑量表(HAMA)、焦虑自评量表(SAS)方面的改善作用均优于中药组、西药组(P<0.05),而在不良反应发生的情况也优于西药组(P<0.01)。结论加味温胆汤是治疗痰热内扰型广泛性焦虑症的有效药物,联合应用可降低西药的副反应。
目的：觀察加味溫膽湯治療痰熱內擾型廣汎性焦慮癥的臨床療效及不良反應。方法將90例符閤納入標準的痰熱內擾型廣汎性焦慮癥患者隨機分為中藥組、西藥組、中西藥組進行觀察,中藥組給予加味溫膽湯每日1劑,早晚分兩次口服；西藥組給予帕囉西汀20 mg,每日1次口服；中西藥組給予加味溫膽湯,每日1劑,帕囉西汀20 mg,每日1次口服。觀察4週後評定療效。結果中西藥聯閤治療在漢密爾頓焦慮量錶(HAMA)、焦慮自評量錶(SAS)方麵的改善作用均優于中藥組、西藥組(P<0.05),而在不良反應髮生的情況也優于西藥組(P<0.01)。結論加味溫膽湯是治療痰熱內擾型廣汎性焦慮癥的有效藥物,聯閤應用可降低西藥的副反應。
목적：관찰가미온담탕치료담열내우형엄범성초필증적림상료효급불량반응。방법장90례부합납입표준적담열내우형엄범성초필증환자수궤분위중약조、서약조、중서약조진행관찰,중약조급여가미온담탕매일1제,조만분량차구복；서약조급여파라서정20 mg,매일1차구복；중서약조급여가미온담탕,매일1제,파라서정20 mg,매일1차구복。관찰4주후평정료효。결과중서약연합치료재한밀이돈초필량표(HAMA)、초필자평량표(SAS)방면적개선작용균우우중약조、서약조(P<0.05),이재불량반응발생적정황야우우서약조(P<0.01)。결론가미온담탕시치료담열내우형엄범성초필증적유효약물,연합응용가강저서약적부반응。
Objective To investigate the effect of Jiawei Wendan decoction(JWD)in the treatment of generalized anxiety disor-der(GAD)with phlegm heat syndrome.Methods Ninety patients with GAD and phlegm heat syndrome were randomly divided into three groups:Group A treated with JWD,group B treated with paroxetine,and group C treated with JWD and paroxetine for 4 weeks. The efficacy was observed.Results The improvement of the Hamilton Anxiety Scale (HAMA)and self rating Anxiety Scale (SAS)in group C were better than those in group A and group B(P< 0.05).The adverse reaction in group C was less than that in group B(P<0.01).Conclusion JWD was effective for the treatment of GAD with phlegm heat syndrome.JWD combined with paroxetine could re-duce the side effects of western medicine.
