中国脑血管病杂志
中國腦血管病雜誌
중국뇌혈관병잡지
CHINESE JOURNAL OF CEREBROVASCULAR DISEASES
2014年
12期
643-649
,共7页
陈妙%余梅%黄建平%朱文宗%支英豪
陳妙%餘梅%黃建平%硃文宗%支英豪
진묘%여매%황건평%주문종%지영호
卒中%吞咽困难%Logistic回归分析%荧光透视检查
卒中%吞嚥睏難%Logistic迴歸分析%熒光透視檢查
졸중%탄인곤난%Logistic회귀분석%형광투시검사
Stroke%Dysphagia%Logistic regression analysis%Video fluoroscopic swallowing study
目的:探讨吞咽障碍患者的临床表现与吞咽荧光透视检查(VFSS)所示结构和功能的相关性。方法连续收集2012年6月—2014年5月浙江中医药大学附属温州市中医院收治的56例卒中后吞咽障碍患者,选择性应用4种不同质地的食物进行测试,分别完成临床吞咽功能评估和VFSS检查,并用SPSS 20.0统计软件对该两种方法的各项观察指标进行单因素分析和多因素Logistic回归分析。结果临床表现与VFSS检查的点对应关系在口腔期有口内食物残留与口唇闭合异常(95%CI:1.430~101.468,P=0.022);软腭上抬差与口腔食物残留(95%CI:1.476~102.033,P=0.020);分次吞咽与口通过时间延长(95%CI:2.616~182.897,P=0.004);舌运动障碍及软腭上抬差与食团形成障碍(95%CI分别为1.468~50.795、1.220~13.825,P值分别为0.017、0.023);食物口角漏出、咽下困难与食团从舌根掉落会厌或气管(95%CI分别为1.146~125.459、1.657~174.400,P值分别为0.038、0.017)。在咽期主要有咽反射减弱与喉上抬程度弱(95%CI:1.150~92.815,P=0.037);咽下困难、吞咽延迟与吞咽反射启动触发时间长(95%CI分别为2.123~37.770、1.233~114.176,P值分别为0.003、0.032);分次吞咽、用力吞咽、哽噎感以及喉上抬差与咽期通过时间长(95%CI分别为1.619~223.316、1.061~31.445、2.834~132.707,P值分别为0.019、0.042、0.003);咽下困难与环咽肌开放不全(95%CI:1.037~24.115,P=0.045);喉上抬程度弱、咽部异物感、吞咽后呛咳与会厌谷或梨状窝滞留或残留(95%CI分别为1.046~13.685、1.116~87.741,P值分别为0.043、0.040);吞咽过程中咳嗽、进食呛咳与误吸(95%CI分别为0.010~0.921、0.037~0.826,P值分别为0.042、0.028)等,均存在明显相关性。结论某些临床症状表现与VFSS检查发现的吞咽功能异常密切相关,借助该规律可更简捷、安全地判断患者吞咽障碍程度及类型,为不能接受VFSS检查的卒中后吞咽障碍患者进行康复治疗作指导。
目的:探討吞嚥障礙患者的臨床錶現與吞嚥熒光透視檢查(VFSS)所示結構和功能的相關性。方法連續收集2012年6月—2014年5月浙江中醫藥大學附屬溫州市中醫院收治的56例卒中後吞嚥障礙患者,選擇性應用4種不同質地的食物進行測試,分彆完成臨床吞嚥功能評估和VFSS檢查,併用SPSS 20.0統計軟件對該兩種方法的各項觀察指標進行單因素分析和多因素Logistic迴歸分析。結果臨床錶現與VFSS檢查的點對應關繫在口腔期有口內食物殘留與口脣閉閤異常(95%CI:1.430~101.468,P=0.022);軟腭上抬差與口腔食物殘留(95%CI:1.476~102.033,P=0.020);分次吞嚥與口通過時間延長(95%CI:2.616~182.897,P=0.004);舌運動障礙及軟腭上抬差與食糰形成障礙(95%CI分彆為1.468~50.795、1.220~13.825,P值分彆為0.017、0.023);食物口角漏齣、嚥下睏難與食糰從舌根掉落會厭或氣管(95%CI分彆為1.146~125.459、1.657~174.400,P值分彆為0.038、0.017)。在嚥期主要有嚥反射減弱與喉上抬程度弱(95%CI:1.150~92.815,P=0.037);嚥下睏難、吞嚥延遲與吞嚥反射啟動觸髮時間長(95%CI分彆為2.123~37.770、1.233~114.176,P值分彆為0.003、0.032);分次吞嚥、用力吞嚥、哽噎感以及喉上抬差與嚥期通過時間長(95%CI分彆為1.619~223.316、1.061~31.445、2.834~132.707,P值分彆為0.019、0.042、0.003);嚥下睏難與環嚥肌開放不全(95%CI:1.037~24.115,P=0.045);喉上抬程度弱、嚥部異物感、吞嚥後嗆咳與會厭穀或梨狀窩滯留或殘留(95%CI分彆為1.046~13.685、1.116~87.741,P值分彆為0.043、0.040);吞嚥過程中咳嗽、進食嗆咳與誤吸(95%CI分彆為0.010~0.921、0.037~0.826,P值分彆為0.042、0.028)等,均存在明顯相關性。結論某些臨床癥狀錶現與VFSS檢查髮現的吞嚥功能異常密切相關,藉助該規律可更簡捷、安全地判斷患者吞嚥障礙程度及類型,為不能接受VFSS檢查的卒中後吞嚥障礙患者進行康複治療作指導。
목적:탐토탄인장애환자적림상표현여탄인형광투시검사(VFSS)소시결구화공능적상관성。방법련속수집2012년6월—2014년5월절강중의약대학부속온주시중의원수치적56례졸중후탄인장애환자,선택성응용4충불동질지적식물진행측시,분별완성림상탄인공능평고화VFSS검사,병용SPSS 20.0통계연건대해량충방법적각항관찰지표진행단인소분석화다인소Logistic회귀분석。결과림상표현여VFSS검사적점대응관계재구강기유구내식물잔류여구진폐합이상(95%CI:1.430~101.468,P=0.022);연악상태차여구강식물잔류(95%CI:1.476~102.033,P=0.020);분차탄인여구통과시간연장(95%CI:2.616~182.897,P=0.004);설운동장애급연악상태차여식단형성장애(95%CI분별위1.468~50.795、1.220~13.825,P치분별위0.017、0.023);식물구각루출、인하곤난여식단종설근도락회염혹기관(95%CI분별위1.146~125.459、1.657~174.400,P치분별위0.038、0.017)。재인기주요유인반사감약여후상태정도약(95%CI:1.150~92.815,P=0.037);인하곤난、탄인연지여탄인반사계동촉발시간장(95%CI분별위2.123~37.770、1.233~114.176,P치분별위0.003、0.032);분차탄인、용력탄인、경일감이급후상태차여인기통과시간장(95%CI분별위1.619~223.316、1.061~31.445、2.834~132.707,P치분별위0.019、0.042、0.003);인하곤난여배인기개방불전(95%CI:1.037~24.115,P=0.045);후상태정도약、인부이물감、탄인후창해여회염곡혹리상와체류혹잔류(95%CI분별위1.046~13.685、1.116~87.741,P치분별위0.043、0.040);탄인과정중해수、진식창해여오흡(95%CI분별위0.010~0.921、0.037~0.826,P치분별위0.042、0.028)등,균존재명현상관성。결론모사림상증상표현여VFSS검사발현적탄인공능이상밀절상관,차조해규률가경간첩、안전지판단환자탄인장애정도급류형,위불능접수VFSS검사적졸중후탄인장애환자진행강복치료작지도。
Objective To investigate the correlation between clinical presentations and the findings of video fluoroscopic swallowing study (VFSS)in patients with post-stroke dysphagia. Methods A total of 56 consecutive patients with post-stroke dysphagia admitted to Wenzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University from June 2012 to May 2014 were enrolled. Four different kinds of food were selectively used to complete clinical assessment of swallowing function and VFSS respectively. The SPSS 20. 0 statistical software was used to perform univariate and multivariate Logistic regression analyses for all observed indexes of the 2 methods. Results there were significant correlations in the point correspondence relation among the clinical manifestations and VFSS in food residue in the mouth and abnormal closure of lips in the oral phase (95%CI 1. 430-101. 468;P=0. 022);poor soft palate elevation and food residue in the mouth (95%CI 1. 476-102. 033;P=0. 020);graded swallowing and piecemeal deglutition with delayed oral transit (95% CI 2. 616 -182. 897;P = 0. 004);tongue movement disorders,poor soft palate elevation and tongue dyskinesia with poor bolus formation (95%CI 1. 468-50. 795,1. 220-13. 825;P=0. 017,0. 023);food leak from the corner of mouth,dysphagia,bolus falling to the epiglottis from the base of tongue or trachea (95%CI 1. 146-125. 459,1. 657-174. 400;P=0.038,0. 017). The weakened pharyngeal reflex with weak laryngeal elevation in the pharyngeal phase (95%CI 1. 150-92. 815;P =0. 037);dysphagia and delayed swallowing with prolonged triggering of swallowing reflex (95%CI 2. 123-37. 770,1. 233-114. 176;P=0. 003,0. 032);graded swallowing,hard swallowing, choking sensation,and poor laryngeal elevation with prolonged pharyngeal transit (95%CI 1. 619-223. 316,1. 061-31. 445,2. 834 -132. 707;P =0. 019,0. 042,and 0. 003);dysphagia and the opening of cricopharyngeal muscle insufficiency (95%CI 1. 037 -24. 115;P =0. 045);weak laryngeal elevation,foreign body sensation in the throat,and choking after swallowing with food retention or residual in vallecula or pyriform sinus (95%CI 1. 046 -13. 685,1. 116 -87. 741;P =0. 043, 0.040);and coughing during swallowing and eating choking or aspiration (95%CI 0. 010-0. 921,0. 037-0. 826;P=0. 042,0. 028). Conclusion Some clinical manifestations are closely correlated with the swallowing dysfunction revealed by VFSS. With the help of this law,it may more simply and safely determine the degree and type of dysphagia in patients,and provide guidance for patients with dysphagia after stroke who can not accept VFSS in the rehabilitation treatment.