中国脑血管病杂志
中國腦血管病雜誌
중국뇌혈관병잡지
CHINESE JOURNAL OF CEREBROVASCULAR DISEASES
2014年
12期
639-642
,共4页
老年人%脑梗死%偏瘫%弥散张量成像%简化Fugl-Meyer运动功能量表
老年人%腦梗死%偏癱%瀰散張量成像%簡化Fugl-Meyer運動功能量錶
노년인%뇌경사%편탄%미산장량성상%간화Fugl-Meyer운동공능량표
Aged%Brain infarction%Hemiparalysis%Diffusion tensor imaging%Fugl-Meyer scale,simplified
目的：探讨磁共振扩散张量成像（DTI）、简化Fugl-Meyer（FM）运动功能量表在老年急性脑梗死偏瘫患者疗效评估中的应用价值。方法前瞻性纳入解放军第三○五医院神经内科2010年11月—2014年4月符合纳入标准的老年急性脑梗死偏瘫患者17例，入院后均给予药物联合偏瘫实用训练技术康复治疗。分别于入院第1、4、12周完成 DTI检查和 FM量表评估。结果3次DTI检查感兴趣区（ROI）健患侧各向异性分数（FA）差值和FM量表评分差异均有统计学意义（F值分别为3.437和3.791，均P＜0.01）。急性脑梗死偏瘫患者DTI中，ROI健患侧FA差值第1周（0.19±0.06）与第4周（0.13±0.04）比较，差异有统计学意义（P<0.05），第4周与第12周（0.13±0.04）差异无统计学意义（P＞0.05）。经药物、康复综合治疗后 FM量表评分：入院第1周[（69±9）分]与第4周[（74±6）分]、第4周与第12周[（82±10）分]比较，差异均有统计学意义（均P＜0.05）。入院第1次DTI中ROI对应的健患侧FA差值与第1阶段（4周）康复治疗前后FM量表评分差值变化呈线性负相关（rs ＝－0.389，P＜0.05）。结论 DTI和FM早期应用于脑梗死偏瘫患者预后评估有一定的预测价值。
目的：探討磁共振擴散張量成像（DTI）、簡化Fugl-Meyer（FM）運動功能量錶在老年急性腦梗死偏癱患者療效評估中的應用價值。方法前瞻性納入解放軍第三○五醫院神經內科2010年11月—2014年4月符閤納入標準的老年急性腦梗死偏癱患者17例，入院後均給予藥物聯閤偏癱實用訓練技術康複治療。分彆于入院第1、4、12週完成 DTI檢查和 FM量錶評估。結果3次DTI檢查感興趣區（ROI）健患側各嚮異性分數（FA）差值和FM量錶評分差異均有統計學意義（F值分彆為3.437和3.791，均P＜0.01）。急性腦梗死偏癱患者DTI中，ROI健患側FA差值第1週（0.19±0.06）與第4週（0.13±0.04）比較，差異有統計學意義（P<0.05），第4週與第12週（0.13±0.04）差異無統計學意義（P＞0.05）。經藥物、康複綜閤治療後 FM量錶評分：入院第1週[（69±9）分]與第4週[（74±6）分]、第4週與第12週[（82±10）分]比較，差異均有統計學意義（均P＜0.05）。入院第1次DTI中ROI對應的健患側FA差值與第1階段（4週）康複治療前後FM量錶評分差值變化呈線性負相關（rs ＝－0.389，P＜0.05）。結論 DTI和FM早期應用于腦梗死偏癱患者預後評估有一定的預測價值。
목적：탐토자공진확산장량성상（DTI）、간화Fugl-Meyer（FM）운동공능량표재노년급성뇌경사편탄환자료효평고중적응용개치。방법전첨성납입해방군제삼○오의원신경내과2010년11월—2014년4월부합납입표준적노년급성뇌경사편탄환자17례，입원후균급여약물연합편탄실용훈련기술강복치료。분별우입원제1、4、12주완성 DTI검사화 FM량표평고。결과3차DTI검사감흥취구（ROI）건환측각향이성분수（FA）차치화FM량표평분차이균유통계학의의（F치분별위3.437화3.791，균P＜0.01）。급성뇌경사편탄환자DTI중，ROI건환측FA차치제1주（0.19±0.06）여제4주（0.13±0.04）비교，차이유통계학의의（P<0.05），제4주여제12주（0.13±0.04）차이무통계학의의（P＞0.05）。경약물、강복종합치료후 FM량표평분：입원제1주[（69±9）분]여제4주[（74±6）분]、제4주여제12주[（82±10）분]비교，차이균유통계학의의（균P＜0.05）。입원제1차DTI중ROI대응적건환측FA차치여제1계단（4주）강복치료전후FM량표평분차치변화정선성부상관（rs ＝－0.389，P＜0.05）。결론 DTI화FM조기응용우뇌경사편탄환자예후평고유일정적예측개치。
Objective To investigate the application value of MR diffusion tensor imaging (DTI ) and simplified Fugl-Meyer (FM ) scale in old patients with acute cerebral infarction and hemiplegia. Methods Seventeen old patients with acute cerebral infarction and hemiplegia who met the inclusion criteria admitted to the Department of Neurology,the 305th Hospital of the People′s Liberation Army from November 2010 to April 2014 were enrolled prospectively. After admission,they were treated with rehabilitation therapy,including drugs in combination with practical training techniques for hemiplegia. After admission,the DTI examination and FM scale assessment were accomplished at the 1st,4th,and 12th weeks,respectively. Results There were significant differences in 3 times of DTI examinations between the contralateral/ipsilateral fractional anisotropy(FA)differences of the region of interest (ROI)and the differences of FM scale score (F=3. 437 and 3. 791 respectively;P<0. 01). In DTI of the acute cerebral infarction patients with hemiplegia,there was significant difference at the 1st week (0. 19 ± 0. 06)between the contralateral and ipsilateral FA difference of ROI compare with the 4th week (0. 13 ± 0. 04),(P>0. 05). There was no significant difference between the 4th and 12th week (0. 13 ± 0. 04)(P>0. 05). After drug and rehabilitation treatment,the FM scale scores showed that there was significant difference between the 1st week after admission (69 ±9)and the 4th week after admission (74 ±6),and between the 4thweek and 12week (82 ±10) (all P<0. 05). At the first time after admission,the corresponding contralateral/ipsilateral FA difference in ROI was negative correlated with that of the FM scale difference change at the first stage (4th week)before and after rehabilitation (rs = -0. 389,P<0.05). Conclusion Early application of DTI and FM in the prognostic evaluation of patients with cerebral infarction and hemiplegia has some predictive values.
