国际护理学杂志
國際護理學雜誌
국제호이학잡지
INTERNATIONAL JOURNAL OF NURSING
2014年
12期
3340-3342
,共3页
降压%肾性高血压%肾功能
降壓%腎性高血壓%腎功能
강압%신성고혈압%신공능
Blood pressure reduction%Renal hypertension%Renal function
目的：探讨降压药服用时间对肾性高血压患者肾功能的影响。方法将192例肾性高血压患者按入院顺序先后随机分为研究组96例和对照组96例。研究组根据患者血压昼夜节律给予调整服药时间，而对照组按传统服药时间给药，随访半年后，观察两组肾性高血压患者夜间收缩压和舒张压下降的有效率及肾功能情况，并进行比较。结果研究组患者夜间收缩压下降有效率为80.21％，舒张压下降有效率为77.08％，而对照组患者夜间收缩压下降有效率为58.33％，舒张压下降有效率为57.29％，两者比较差异均有统计学意义（P＜0.01），研究组患者肾功能各项指标均较好，两组比较差异有统计学意义（P＜0.01）。结论掌握人体生理病理的时间节律，对肾性高血压患者实施适时给药，能明显有效、全程平稳降压，对改善肾性高血压患者降压效果以及保护其肾功能具有非常重要的现实意义。
目的：探討降壓藥服用時間對腎性高血壓患者腎功能的影響。方法將192例腎性高血壓患者按入院順序先後隨機分為研究組96例和對照組96例。研究組根據患者血壓晝夜節律給予調整服藥時間，而對照組按傳統服藥時間給藥，隨訪半年後，觀察兩組腎性高血壓患者夜間收縮壓和舒張壓下降的有效率及腎功能情況，併進行比較。結果研究組患者夜間收縮壓下降有效率為80.21％，舒張壓下降有效率為77.08％，而對照組患者夜間收縮壓下降有效率為58.33％，舒張壓下降有效率為57.29％，兩者比較差異均有統計學意義（P＜0.01），研究組患者腎功能各項指標均較好，兩組比較差異有統計學意義（P＜0.01）。結論掌握人體生理病理的時間節律，對腎性高血壓患者實施適時給藥，能明顯有效、全程平穩降壓，對改善腎性高血壓患者降壓效果以及保護其腎功能具有非常重要的現實意義。
목적：탐토강압약복용시간대신성고혈압환자신공능적영향。방법장192례신성고혈압환자안입원순서선후수궤분위연구조96례화대조조96례。연구조근거환자혈압주야절률급여조정복약시간，이대조조안전통복약시간급약，수방반년후，관찰량조신성고혈압환자야간수축압화서장압하강적유효솔급신공능정황，병진행비교。결과연구조환자야간수축압하강유효솔위80.21％，서장압하강유효솔위77.08％，이대조조환자야간수축압하강유효솔위58.33％，서장압하강유효솔위57.29％，량자비교차이균유통계학의의（P＜0.01），연구조환자신공능각항지표균교호，량조비교차이유통계학의의（P＜0.01）。결론장악인체생리병리적시간절률，대신성고혈압환자실시괄시급약，능명현유효、전정평은강압，대개선신성고혈압환자강압효과이급보호기신공능구유비상중요적현실의의。
Objective To explore the effect of taking blood pressure reduction medicine at different time on kidney function of pa-tients with renal hypertension.Methods A total of 192 cases of the patients with renal hypertension were divided into study group with 96 cases and control group with 96 cases at random in order.The study group used the adjusting time for taking medical according to the patients suffered high blood in the dynamic day and night but the control group used the medicine depended on the traditional taking medicine time only.After the half year, the drop effectiveness rates of night mean systolic blood pressure and diastolic blood pressure and renal function of patients were compared between two groups.Results The drop effectiveness rate of night mean systolic blood pressure of the patients in the study group was 80.21%;The drop effectiveness rate of diastolic blood pressure of the patients was 77.08% but in the control group they were 58.33%, 57.29%respectively.The differences were significantly ( P<0.01 ) .Conclusions Mastering time rhythm of the body physiological pathology, giving medicine to the patients with renal hypertension suitably can evidently drop the blood pressure effectively.It has a very important realistic meaning for the improvement of the patients with renal hypertension effectively to protect the renal function.
