上海医药
上海醫藥
상해의약
SHANGHAI MEDICAL & PHARMACEUTICAL JOURNAL
2014年
23期
73-80
,共8页
齐墩果酸%熊果酸%抗动脉粥样硬化%抗高血脂%血管保护作用
齊墩果痠%熊果痠%抗動脈粥樣硬化%抗高血脂%血管保護作用
제돈과산%웅과산%항동맥죽양경화%항고혈지%혈관보호작용
oleanolic acid%ursolic acid%antiatherosclerosis%antihyperlipidemia%vascular protective effects
齐墩果酸和熊果酸是化学立体结构相同的同分异构体，广泛存在于各种蔬菜、水果和中草药中，具有广泛的生物活性如保肝、抗炎、抗微生物、抗糖尿病和抗肿瘤作用等。本文从抗高血脂、抗氧化、抗炎、抗血小板聚集、保护血管内膜和抑制血管平滑肌细胞增生等方面论述齐墩果酸和熊果酸的抗动脉粥样硬化作用。
齊墩果痠和熊果痠是化學立體結構相同的同分異構體，廣汎存在于各種蔬菜、水果和中草藥中，具有廣汎的生物活性如保肝、抗炎、抗微生物、抗糖尿病和抗腫瘤作用等。本文從抗高血脂、抗氧化、抗炎、抗血小闆聚集、保護血管內膜和抑製血管平滑肌細胞增生等方麵論述齊墩果痠和熊果痠的抗動脈粥樣硬化作用。
제돈과산화웅과산시화학입체결구상동적동분이구체，엄범존재우각충소채、수과화중초약중，구유엄범적생물활성여보간、항염、항미생물、항당뇨병화항종류작용등。본문종항고혈지、항양화、항염、항혈소판취집、보호혈관내막화억제혈관평활기세포증생등방면논술제돈과산화웅과산적항동맥죽양경화작용。
Oleanolic acid (OA) and ursolic acid (UA) are the isomers with the same stereochemical structure, which wildly exist in vegetables, fruits and Chinese herbal medicines and possess widespread bioactivities such as hepatoprotection, anti-inlfammatory, antimicrobial, anti-diabetic, antitumor action and so on. In this article, antiatherosclerotic effects of OA and UA are reviewed from the aspects of antihyperlipidemia, antioxidation, anti-inlfammatory, anti-platelet aggregation, protection of vascular intima, and inhibition of the proliferation of vascular smooth muscle cells.
