CAJ | 학술논문

目的：：分析腹腔镜和开腹大肠癌根治术的长期疗效和安全性。方法：收集我院2009年5月至2011年5月期间诊治的大肠癌患者200例作为研究对象，采用随机分组的方式将患者分为观察组与对照组，每组患者各100例。对照组采用常规开腹手术治疗，观察组采用腹腔镜手术治疗，对两组患者的临床效果进行分析对比。结果：研究结果显示，两组患者手术时间比较无明显差异( P>0.05)，但观察组患者并发症发生率明显低于对照组(P<0.05)，肛门排气时间明显短于对照组(P<0.05)，术中出血量明显少于对照组( P<0.05)，观察组患者围手术期死亡率略高于对照组，但组间比较差异无统计学意义(P>0.05)；对两组患者实施为期三年的随访发现，观察组中有46例存活，生存率为92.0%，对照组中有42例存活，生存率为84.0%，观察组三年生存率略高于对照组，但组间比较差异不具统计学意义( P>0.05)。结论：腹腔镜大肠癌根治术的长期疗效和安全性优于开腹手术，值得在临床应用上推广。
목적：：분석복강경화개복대장암근치술적장기료효화안전성。방법：수집아원2009년5월지2011년5월기간진치적대장암환자200례작위연구대상，채용수궤분조적방식장환자분위관찰조여대조조，매조환자각100례。대조조채용상규개복수술치료，관찰조채용복강경수술치료，대량조환자적림상효과진행분석대비。결과：연구결과현시，량조환자수술시간비교무명현차이( P>0.05)，단관찰조환자병발증발생솔명현저우대조조(P<0.05)，항문배기시간명현단우대조조(P<0.05)，술중출혈량명현소우대조조( P<0.05)，관찰조환자위수술기사망솔략고우대조조，단조간비교차이무통계학의의(P>0.05)；대량조환자실시위기삼년적수방발현，관찰조중유46례존활，생존솔위92.0%，대조조중유42례존활，생존솔위84.0%，관찰조삼년생존솔략고우대조조，단조간비교차이불구통계학의의( P>0.05)。결론：복강경대장암근치술적장기료효화안전성우우개복수술，치득재림상응용상추엄。
Objective:To analyze the long-term efficacy and safety of laparoscopic and open colorectal for cancer radical. Method:200 cases of colorectal cancer patients treated in our hospital from May 2009 to May 2011 were collected as the research objects, and the patients were randomly divided into observation group and control group, 100 cases in each group. The patients in the control group were treated by using conventional laparotomy surgery, and the patients in the observation group were treated with laparoscopic sur-gery, and the clinical effect on the patients of two groups was analyzed and compared. Result:There was no significant difference in operation time between two groups ( P > 0.05) , but the complication rate of the ob-servation group was significantly lower than that of the control group (P < 0.05), the anal exhaust time in the observation group was significantly shorter than that in the control group ( P < 0.05) , the intraoperative blood loss in the observation group was significantly less than that in the control group ( P < 0.05) , and the perioperative mortality of the observation group was slightly higher than that of the control group, but there was no statistically significant difference compared between groups ( P > 0.05); For two groups of patients with a three-year follow-up 46 cases survived in the observation group, the survival rate was 92.0%, 42 ca-ses survived in the control group, the survival rates was 84.0%, the 3-year survival rate of the observation group was slightly higher than that of the control group, but the difference was not significant compared be-tween groups ( P > 0.05) . Conclusion:The long-term efficacy and safety of laparoscopic colorectal cancer radical is superior to laparotomy, and it is worth for popularization in clinical application.