CAJ | 학술논문

近年来，白介素作为鱼类重要的免疫细胞因子，已进行了广泛研究，相继获得鲤（Cyprinus carpio）和小斑点猫鲨（Scyliorhinus canicula）的IL-1β全长基因及虹鳟（Oncorhynchus mykiss）的IL-1β受体基因、河鲀（Tak－ifugu rubripes）IL-4和斑马鱼（Danio rerio）IL-4基因及其受体、鲤IL-10基因。本文综述了IL-1β、IL-4、IL-10基因的克隆与表达等最新资料。
근년래，백개소작위어류중요적면역세포인자，이진행료엄범연구，상계획득리（Cyprinus carpio）화소반점묘사（Scyliorhinus canicula）적IL-1β전장기인급홍준（Oncorhynchus mykiss）적IL-1β수체기인、하돈（Tak－ifugu rubripes）IL-4화반마어（Danio rerio）IL-4기인급기수체、리IL-10기인。본문종술료IL-1β、IL-4、IL-10기인적극륭여표체등최신자료。
In the past years, interleukin as an important class of immune cytokines in fish has already been studied extensively and many important progresses of the interleukin have been made including the cloning of common carp(Cyprinus carpio )and small spot-ted cat shark (Scyliorhinus canicula) IL-1βfull-length gene, rainbow trout (Oncorhynchus mykiss) IL-1β. The cloning of IL-1β, IL-4, IL-10 genes and expression are summarized.