CAJ | 학술논문

目的：了解多重耐药鲍曼不动杆菌在不同临床科室的分布情况及其外排泵基因型。方法对分离的96株多重耐药鲍曼不动杆菌在不同临床科室的分布情况进行统计分析，采用PCR法对其外排泵基因进行检测。结果96株多重耐药鲍曼不动杆菌分布在ICU 52株、呼吸内科18株、烧伤科9株、肿瘤科6株、普外科4株、肾内科2株、心内科2株、儿科2株、精神科1株。96株多重耐药鲍曼不动杆菌检测到adeB、adeR、adeS、adeJ、adeE、adeM基因者分别有33、32、33、33、0、33株；分布在ICU的52株多重耐药鲍曼不动杆菌检测到adeB、adeR、adeS、adeJ、adeE、abeM基因者分别有18、16、18、18、0、18株；分布在呼吸内科的18株多重耐药鲍曼不动杆菌检测到adeB、adeR、adeS、adeJ、adeE、abeM基因者分别有9、8、8、8、0、8株。结论多重耐药鲍曼不动杆菌主要分布在ICU和呼吸内科，其外排泵基因型主要为adeB、adeR、adeS、adeJ、adeM，这是鲍曼不动杆菌发生多重耐药的重要因素。
목적：료해다중내약포만불동간균재불동림상과실적분포정황급기외배빙기인형。방법대분리적96주다중내약포만불동간균재불동림상과실적분포정황진행통계분석，채용PCR법대기외배빙기인진행검측。결과96주다중내약포만불동간균분포재ICU 52주、호흡내과18주、소상과9주、종류과6주、보외과4주、신내과2주、심내과2주、인과2주、정신과1주。96주다중내약포만불동간균검측도adeB、adeR、adeS、adeJ、adeE、adeM기인자분별유33、32、33、33、0、33주；분포재ICU적52주다중내약포만불동간균검측도adeB、adeR、adeS、adeJ、adeE、abeM기인자분별유18、16、18、18、0、18주；분포재호흡내과적18주다중내약포만불동간균검측도adeB、adeR、adeS、adeJ、adeE、abeM기인자분별유9、8、8、8、0、8주。결론다중내약포만불동간균주요분포재ICU화호흡내과，기외배빙기인형주요위adeB、adeR、adeS、adeJ、adeM，저시포만불동간균발생다중내약적중요인소。
Objective To investigate the distribution of multidrug-resistant Acinetobacter baumannii in different clini-cal department and to indicate the efflux pump genotype of multidrug-resistant Acinetobacter baumannii .Methods A total of 96 separated multidrug-resistant Acinetobacter baumannii specimens , which were collected from different clinic depart-ments, were involved to analyse their clinic distributions .The efflux pump genetype of Acinetobacter baumannii was identi-fied by method of PCR .Results It was found that 52 Acinetobacter baumannii specimens from ICU , 18 from respiratory medicine department , 9 from burns surgery department , 6 from oncology department , 4 from general surgery department , 2 from nephrology department , 2 from cardiology department , 2 from pediatrics department , 2 from psychiatry department . The case of adeB, adeR, adeS, adeJ, adeE, adeM efflux pump genetype in all 96 multidrug-resistant Acinetobacter bau-mannii specimens was 33, 32, 33, 33, 0 and 33, respectively.The case of adeB, adeR, adeS, adeJ, adeE, adeM efflux pump genetype in 52 specimens derived from ICU was 18, 16, 18, 18, 0 and 18, respectively.The case of adeB, adeR, adeS, adeJ, adeE, adeM efflux pump genetype in 18 specimens derived from respiratory medicine department was 9, 8, 8, 8, 0 and 8, respectively.Conclusions Multidrug-resistant Acinetobacter baumannii is mainly distributed in ICU and re-spiratory medicine department .The major genetype of Acinetobacter baumannii are adeB , adeR, adeS, adeJ and adeM, which are the main reasons contribute to the multidrug-resistance of Acinetobacter baumannii .