中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
EVALUATION AND ANAL YSIS OF DRUG-USE IN HOSPITALS OF CHINA
2014年
12期
1120-1122
,共3页
抗菌药物%专项整治%烧伤科%合理用药
抗菌藥物%專項整治%燒傷科%閤理用藥
항균약물%전항정치%소상과%합리용약
Antibiotics%Special rectification%Burn ward%Rational use of drugs
目的：探讨开展抗菌药物专项整治活动对中山市人民医院（以下简称为“我院”）烧伤科住院患者使用抗菌药物情况的影响。方法：回顾性统计、分析我院烧伤科开展专项整治前、后出院患者的临床资料和抗菌药物使用情况。结果：经过专项整治，我院烧伤科住院患者抗菌药物使用率从整治前的100?00％下降至96?33％；抗菌药物销售金额占药品销售总金额的比例从整治前的61?78％下降至25?56％；抗菌药物使用强度（AUD）从整治前的162?35 DDDs／（100人·d）下降至55?78 DDDs／（100人·d）；抗菌药物的总DDDs由3335?55下降至1262?72；病原菌对常用抗菌药物的耐药率降低；单药使用率从76?27％上升至83?18％，但二联用药率和三联用药率的下降幅度不大，分别从16?10％下降至8?41％、从5?09％下降至4?68％。结论：专项整治对合理使用抗菌药物有明显的促进作用，但仍需加强对使用抗菌药物的监管。
目的：探討開展抗菌藥物專項整治活動對中山市人民醫院（以下簡稱為“我院”）燒傷科住院患者使用抗菌藥物情況的影響。方法：迴顧性統計、分析我院燒傷科開展專項整治前、後齣院患者的臨床資料和抗菌藥物使用情況。結果：經過專項整治，我院燒傷科住院患者抗菌藥物使用率從整治前的100?00％下降至96?33％；抗菌藥物銷售金額佔藥品銷售總金額的比例從整治前的61?78％下降至25?56％；抗菌藥物使用彊度（AUD）從整治前的162?35 DDDs／（100人·d）下降至55?78 DDDs／（100人·d）；抗菌藥物的總DDDs由3335?55下降至1262?72；病原菌對常用抗菌藥物的耐藥率降低；單藥使用率從76?27％上升至83?18％，但二聯用藥率和三聯用藥率的下降幅度不大，分彆從16?10％下降至8?41％、從5?09％下降至4?68％。結論：專項整治對閤理使用抗菌藥物有明顯的促進作用，但仍需加彊對使用抗菌藥物的鑑管。
목적：탐토개전항균약물전항정치활동대중산시인민의원（이하간칭위“아원”）소상과주원환자사용항균약물정황적영향。방법：회고성통계、분석아원소상과개전전항정치전、후출원환자적림상자료화항균약물사용정황。결과：경과전항정치，아원소상과주원환자항균약물사용솔종정치전적100?00％하강지96?33％；항균약물소수금액점약품소수총금액적비례종정치전적61?78％하강지25?56％；항균약물사용강도（AUD）종정치전적162?35 DDDs／（100인·d）하강지55?78 DDDs／（100인·d）；항균약물적총DDDs유3335?55하강지1262?72；병원균대상용항균약물적내약솔강저；단약사용솔종76?27％상승지83?18％，단이련용약솔화삼련용약솔적하강폭도불대，분별종16?10％하강지8?41％、종5?09％하강지4?68％。결론：전항정치대합리사용항균약물유명현적촉진작용，단잉수가강대사용항균약물적감관。
OBJECTIVE: To evaluate the effects of special rectification on rational use of antibiotics in our hospital. METHODS: The clinical data and the antibiotic use of the discharged burn patients before and after rectification( Jul.?Sept. period of 2010 versus Jul.?Sept. period of 2012 ) were analyzed retrospectively. RESULTS:The rate( mean value) of antibiotic use was reduced from 100?00% before rectification to 96?33% after rectification;the proportion of antibiotic cost in total drug cost decreased from 61?78% to 25?56%; AUD decreased from 162?35 DDDs/(100 persons·day) to 55?78 DDDs/(100 persons·day); the total DDDs of antibacterials decreased from 3 335?55 to 1 262?72 . The resistance rates of pathogens to common antibiotics were reduced;the rate of single?drug use was up from 76?27% to 83?18% after rectification, but the rate of two?drug and three?drug use was down from 16?10% to 8?41% and that of three?drug was down from 5?09% to 4?68%. CONCLUSIONS: The special rectification activity promoted the antibiotic use and achieved primary outcome in burn department of our hospital;however, the rate of antibiotic use, AUD and the proportion of antibiotics in total in terms of drug cost failed to meet the ideal requirements;therefore, strengthened supervision on antibiotic use remains to be done.
