CAJ | 학술논문

目的：探讨综合护理干预对造血干细胞移植患者口腔黏膜炎影响的研究。方法：将174例造血干细胞移植患者随机分为干预组和对照组，每组87例。干预组在常规护理基础上给予综合护理干预，对照组给予常规护理，比较两组预处理后1周口腔黏膜炎发生及严重程度情况。结果：综合护理干预组与对照组的口腔黏膜炎发生率分别为54.47%和68.97%，干预前后口腔黏膜炎的发生率差异无统计学意义(x2=2.47，P＞0.05)。但综合护理干预可以明显减轻患者口腔黏膜炎发生的严重程度，有利于控制其炎症发展，促进愈合。结论：综合护理干预能有效减少造血干细胞移植患者口腔黏膜炎发生、发展程度，提高患者造血干细胞移植后的生活质量。
목적：탐토종합호리간예대조혈간세포이식환자구강점막염영향적연구。방법：장174례조혈간세포이식환자수궤분위간예조화대조조，매조87례。간예조재상규호리기출상급여종합호리간예，대조조급여상규호리，비교량조예처리후1주구강점막염발생급엄중정도정황。결과：종합호리간예조여대조조적구강점막염발생솔분별위54.47%화68.97%，간예전후구강점막염적발생솔차이무통계학의의(x2=2.47，P＞0.05)。단종합호리간예가이명현감경환자구강점막염발생적엄중정도，유리우공제기염증발전，촉진유합。결론：종합호리간예능유효감소조혈간세포이식환자구강점막염발생、발전정도，제고환자조혈간세포이식후적생활질량。
Objective: To discuss the influence of comprehensive nursing intervention on patient’s oral mucositis with hematopoietic stem cell transplantation. Methods:One hundred and seventy four examples of patients with hematopoietic stem cell transplantation were equally and randomly divided into two groups, which are intervention group and control group. The usual care was given to the control group, while both the usual care and comprehensive nursing intervention were given to the intervention group. The comparative study of the occurrence and severity degree of oral mucositis in these two groups after one week pretreatment was conducted. Results:The occurrence rate of oral mucositis in intervention group and control group was 54.47%and 68.97%respectively. And there is no obvious significance of the occurrence rate before and after the intervention(x2=2.47, P>0.05). Nevertheless, the comprehensive nursing intervention could significantly lessen the severity of oral mucositis, and help to control the inflammation and promote healing. Conclusion:comprehensive nursing intervention could effectively reduce the occurrence degree of oral mucositis in the patients with hematopoietic stem cell transplantation.