CAJ | 학술논문

目的：探讨两种免疫分析系统检测自身免疫性甲状腺功能减退(甲减)患者血清促甲状腺激素(TSH)结果的一致性。方法：采用宝太BIOT-YG-I与罗氏E601免疫分析系统，检测80例自身免疫性甲减患者和40例正常人血清的TSH水平，通过Kappa检验分析两种系统检测结果的一致程度，并利用线性回归分析两种系统定量检测TSH的相对偏差。结果：两种系统检测TSH结果的符合率及一致性较高；两系统间TSH定量测定结果直线相关性良好(r≥0.975)，在相应医学参考水平浓度测定结果的相对偏差均可被临床接受。结论：两种免疫分析系统检测TSH的结果一致性较高。
목적：탐토량충면역분석계통검측자신면역성갑상선공능감퇴(갑감)환자혈청촉갑상선격소(TSH)결과적일치성。방법：채용보태BIOT-YG-I여라씨E601면역분석계통，검측80례자신면역성갑감환자화40례정상인혈청적TSH수평，통과Kappa검험분석량충계통검측결과적일치정도，병이용선성회귀분석량충계통정량검측TSH적상대편차。결과：량충계통검측TSH결과적부합솔급일치성교고；량계통간TSH정량측정결과직선상관성량호(r≥0.975)，재상응의학삼고수평농도측정결과적상대편차균가피림상접수。결론：량충면역분석계통검측TSH적결과일치성교고。
Objective: To compare the results of TSH serum samples in patients with autoimmune hypothyroidism detected by two different immune analyze systems BIOT-YG-I and Roche E601. Methods:TSH in serum samples from 80 patients with autoimmune hypothyroidism and 40 normal controls were quantified by BIOT-YG-I and Roche E601 systems. Kappa statistic was used to analyze the agreement between the results from two immune analyze systems. The relatively deviation at medical reference level of the quantitative results of TSH were further studied using linear regressive analysis. Results: The quantitative results from two immune analyze systems presents good accordance rate and the agreement as well as a significant linear correlation (r≥0.975). TSH quantitative results from two systems are both clinically acceptable at medical reference level. Conclusion:The consistency of two immune analyze systems is high for detecting TSH serum.