CAJ | 학술논문

核能与核技术的应用给人类带来巨大便利的同时，也大大增加了人们遭受辐射损伤的潜在性风险。抗辐射药物可减少电离辐射损伤引起的发病率和死亡率，长期以来人们致力于抗辐射药物的研究与开发，关于低毒性和保护效果好的辐射防护剂研究倍受关注，并且筛选出了一批具有良好抗辐射作用的候选药物。其中，生物制品类抗辐射药物作为急性辐射综合征预防或治疗药物展现了良好的应用前景，本文主要对近年来进展较快的生物制品类抗辐射药物的研究现状进行综述。
핵능여핵기술적응용급인류대래거대편리적동시，야대대증가료인문조수복사손상적잠재성풍험。항복사약물가감소전리복사손상인기적발병솔화사망솔，장기이래인문치력우항복사약물적연구여개발，관우저독성화보호효과호적복사방호제연구배수관주，병차사선출료일비구유량호항복사작용적후선약물。기중，생물제품류항복사약물작위급성복사종합정예방혹치료약물전현료량호적응용전경，본문주요대근년래진전교쾌적생물제품류항복사약물적연구현상진행종술。
The application of nuclear energy and nuclear technology has brought great convenience to human beings, but also greatly increases the potential risk of people exposed to radiation injury. Radioprotectants could reduce morbidity or mortality produced by ionizing irradiation. Substantial efforts to develop medically effective radioprotectant were initiated for a long time. The research of radioprotectant with good protection effect and low toxicity has become the focus, and some candidate drugs have been found. The biological agents, as the preventive and therapeutic medical measures for the acute radiation syndrome, have exhibited a good prospect. This review is an attempt to provide vital information about the current status of some representative biological radioprotectants and their future perspective.